Results 161 to 170 of about 699,479 (388)

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

open access: yesAdvanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su   +18 more
wiley   +1 more source

The generalizability of empirically derived syndromes of collateral‐reported elder psychopathology across 11 societies

open access: gold, 2021
Masha Y. Ivanova   +23 more
openalex   +2 more sources

Laser‐Architected Shape‐Configurable Vertical Graphene Thermoacoustic Loudspeakers for 3D Acoustic Emission

open access: yesAdvanced Science, EarlyView.
A dual‐laser‐architected vertical graphene film enables high‐performance, morphologically reconfigurable thermoacoustic loudspeakers.The vertically aligned graphene structures combine efficient heat dissipation, thickness‐independent SPL, and kirigami‐driven 3D transformations, offering shape‐programmable, stretchable, and omnidirectional acoustic ...
TaeGyeong Lim   +11 more
wiley   +1 more source

Coronary collaterals [PDF]

open access: yesEuropean Heart Journal, 2005
Marc, Dewey, Hans-Peter, Dübel
openaire   +2 more sources

The Collateral Channel under Imperfect Debt Enforcement [PDF]

open access: yes
Does a country’s ability to enforce debt contracts affect the sensitivity of economic activity to collateral values? To answer this question, we introduce a novel industry-specific measure of real asset redeployability - the ease with which real assets ...
Mathieu Grobéty, Toni Beutler
core  

Nanozyme Microrobots: Programmable Spatiotemporal Catalysis for Targeted Therapy and Diagnostics

open access: yesAdvanced Science, EarlyView.
This review presents nanozyme microrobots as emerging catalytic systems that integrate mobility, external actuation, and adaptive reactivity to achieve precise biochemical functions. By examining mobility‐regulated catalysis, spatial targeting, integrated designs, and translational demonstrations, the article highlights how nanozyme robotics enables ...
Hong Huy Tran   +5 more
wiley   +1 more source

Angiogenesis and surgical or endovascular enhancement of noncoronary collateral circulation: A new research field [PDF]

open access: bronze, 2010
Marco Picichè   +4 more
openalex   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

open access: yesAdvanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin   +15 more
wiley   +1 more source

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