Results 91 to 100 of about 966,331 (317)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Collecting Cans: Number and Algebra

open access: yes, 2018
In this book Millie the Mathematician helps us solve addition problems using a range of strategies.
Hall, Randall   +2 more
core  

Collecting Net. v. 17, 1942 [PDF]

open access: yes, 1942
A weekly publication devoted to the scientific work at marine biological laboratories.Vol. 17. 5 numbered issues published from July 4-Aug. 29, 1942. Numbered both as issues 1-5 and issues 148-152.
Marine Biological Laboratory (Woods Hole MA)
core  

Market Discipline in Commercial Banking: Evidence from the Market for Bank Equity

open access: yesLahore Journal of Economics
This study presents empirical evidence of market discipline, using a panel dataset of listed banks on the Karachi Stock Exchange. We construct multiple riskbased measures from the stock prices between 2004 and 2009 to determine whether an increase in ...
Ayesha Afzal, Nawazish Mirza
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

New Collecting Awards: modernist jewellery

open access: yes, 2015
Earlier this year Sarah Rothwell won funding from the New Collecting Awards to develop a collection of modernist jewellery at National Museums Scotland.
Rothwell, Sarah
core  

Noteworthy Collections

open access: yesMadroño, 2008
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +5 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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