Results 121 to 130 of about 2,890,044 (358)
Designing Collectives, Designing Collectivity
, 2023 Architecture’s Afterlife interviews have defied any rigid categorization, supporting the argument that the mentioned 38% is not “other than architecture,” or at least not completely. This percentage is understood as practitioners whose work is complementary, even instrumental to architecture.
openaire +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A consensus based network intrusion detection system
, 2015 Network intrusion detection is the process of identifying malicious behaviors that target a network and its resources. Current systems implementing intrusion detection processes observe traffic at several data collecting points in the network but ...
Curtis, Philip +2 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
RIHA Journal, 2011 W drugiej połowie XIX wieku w europejskim kolekcjonerstwie wyróżniała się tendencja naukowego podejścia do zbieractwa. Kolekcjonerzy nawiązywali kontakty ze znawcami i badaczami sztuki, aby tworzyć zbiory najwyższej klasy.
Kłudkiewicz, Kamila
doaj
Science Secrets under the Ice [PDF]
, 2007 Lora Koenig ’99 spent a summer in Antarctica collecting data about Earth’s ...
Davis, Laura
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Cost-Effective HITs for Relative Similarity Comparisons [PDF]
, 2014 Similarity comparisons of the form "Is object a more similar to b than to c?" are useful for computer vision and machine learning applications. Unfortunately, an embedding of $n$ points is specified by $n^3$ triplets, making collecting every triplet an ...
Belongie, Serge J. +2 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source