Results 101 to 110 of about 15,464,746 (377)

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Collection and rearing of earthworms [PDF]

open access: yes, 2009
Earthworm experimentation requires a source of supply. This may come from field-collection, purchase from a supplier, or from breeding of stock. The mode of obtaining the animals may be determined by the type of experimentation, but must not compromise ...
Butt, Kevin Richard
core  

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Also looking like Limulus? – retinula axons and visual neuropils of Amblypygi (whip spiders)

open access: yesFrontiers in Zoology, 2018
Background Only a few studies have examined the visual systems of Amblypygi (whip spiders) until now. To get new insights suitable for phylogenetic analysis we studied the axonal trajectories and neuropil architecture of the visual systems of several ...
Tobias Lehmann, Roland R. Melzer
doaj   +1 more source

Legal Archetypes and Metadata Collection [PDF]

open access: yes, 2017
In discussions of state surveillance, the values of privacy and security are often set against one another, and people often ask whether privacy is more important than national security.2 I will argue that in one sense privacy is more important than ...
Rubel, Alan
core  

Collection analysis for Horn clause programs [PDF]

open access: yes, 2006
We consider approximating data structures with collections of the items that they contain. For examples, lists, binary trees, tuples, etc, can be approximated by sets or multisets of the items within them.
Miller, Dale
core   +4 more sources

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Classification of data collection methods (= Deliverable 3.1 of the OrganicDataNetwork project - Report on collection methods) [PDF]

open access: yes, 2013
In this report, a number of evaluation and quality criteria for data collection and compilation methods were defined. The results of an online survey on all existing organic market data collection methods in Europe were compiled and assessed ...
Feldmann , Corinna, Hamm, Ulrich
core  

Collected Essays

open access: yes, 1893
Known as 'Darwin's Bulldog', the biologist Thomas Henry Huxley (1825–95) was a tireless supporter of the evolutionary theories of his friend Charles Darwin. Huxley also made his own significant scientific contributions, and he was influential in the development of science education despite having had only two years of formal schooling.
openaire   +6 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

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