Results 181 to 190 of about 13,442,224 (337)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Predictors of carotenoid status in New Zealand children using carotenoid reflection score: a cross-sectional study. [PDF]

Asia Pac J Clin Nutr
Rapson J, Rush E, McLean R, Fuavao K, Wall C, Eyles H.   +5 more
europepmc   +1 more source

Derailment Detection and Data Collection in Freight Trains, Based on a Wireless Sensor Network

, 2016
Massimo Macucci, Stefano Di Pascoli, Paolo Marconcini, Bernardo Tellini   +3 more
openalex   +2 more sources

The unknown planktonic foraminiferal pioneer Henry A. Buckley and his collection at The Natural History Museum, London [PDF]

, 2016
Marina C. Rillo, John E. Whittaker, Thomas H. G. Ezard, Andy Purvis, Andrew S. Henderson, Stephen Stukins, C. Giles Miller   +6 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Human papillomavirus self-collection: The long road from scientific evaluation to implementation in screening programs. [PDF]

CA Cancer J Clin
Wentzensen N, Baena A.
europepmc   +1 more source

Collecting, Collectibles, Collectors and Collections

Les carnets de la bande dessinée, 2010
openaire   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Blastic plasmacytoid dendritic cell neoplasm (BPDCN): international, multi-center collaboration and global registry program. [PDF]

Discov Oncol
Voskanyan A, Badikyan M, Konopleva M, Alencar A, Ivanyan A, Owen C, Sergi CM, Peng CT, Kazandjian D, Taylor J, Tekkesin F, Ghali H, Bedirian K, Martelli MP, Attardi E, Voso MT, Abramashvili M, Al-Jadiry MF, Michael M, Su MY, Martirosyan N, Ghahramanyan N, Totogashvili N, Kotoucek PP, Kebudi R, Ohannessian R, Papyan R, Hovsepyan S, Elashwah S, Bakhshi S, Bardakhchyan S, Danelyan S, El-Ashwah S, Kutluk T, Tuğcu D, Alhuraiji A, Lazaris V, Tamamyan G, Pemmaraju N.   +38 more
europepmc   +1 more source

Portable Automation of Static Chamber Sample Collection for Quantifying Soil Gas Flux [PDF]

, 2018
Morgan P. Davis, Tyler A. Groh, Timothy B. Parkin, Ryan J. Williams, Thomas M. Isenhart, Kirsten Hofmockel   +5 more
openalex   +1 more source