Results 71 to 80 of about 13,442,224 (337)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Metabolomics Markers of COVID-19 Are Dependent on Collection Wave [PDF]

open access: gold, 2022
Holly-May Lewis   +14 more
openalex   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Seventeen new genera of microgastrine parasitoid wasps (Hymenoptera, Braconidae) from tropical areas of the world

open access: yesJournal of Hymenoptera Research, 2018
As part of comprehensive studies on the world fauna of microgastrine parasitoid wasps (Hymenoptera: Braconidae) 17 new genera and 29 new species are described from the Afrotropical, Australasian, Neotropical and Oriental regions.
Jose Fernandez-Triana   +1 more
doaj   +3 more sources

Solar energy collection system [PDF]

open access: yes, 1979
A fixed, linear, ground-based primary reflector having an extended curved sawtooth-contoured surface covered with a metalized polymeric reflecting material, reflects solar energy to a movably supported collector that is kept at the concentrated line ...
Miller, C. G., Stephens, J. B.
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

An Exceptional Collection For Khovanov Homology

open access: yes, 2014
The Temperley-Lieb algebra is a fundamental component of SU(2) topological quantum field theories. We construct chain complexes corresponding to minimal idempotents in the Temperley-Lieb algebra.
Bakalov   +6 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Historical reference collection : 1976 - 2007 [PDF]

open access: yes, 2010
Another accruing and evolving collection holding published university documents (documents made publicly available) and non-official institutional records, plus 'grey literature' and ephemera relating to UB and its forerunner institutions.
University of Botswana, Library
core  

CCT4 promotes tunneling nanotube formation

open access: yesFEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto   +3 more
wiley   +1 more source

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