Results 51 to 60 of about 9,102,493 (344)
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Supporting the Upscaling of Citizen Science to Address Global Challenges
In May 2024, a workshop was held as part of the European Citizen Science Association (ECSA) 2024 conference in Vienna to explore the creation of transnational communities to upscale citizen science, to address global issues as outlined by the European ...
James Christopher Sprinks +12 more
doaj +1 more source
Social identities facilitate and encapsulate action-relevant constructs: A test of the social identity model of collective action [PDF]
Three studies explore the recently elaborated social identity model of collective action (SIMCA) and an alternative, the encapsulated model of social identity in collective action (EMSICA).
Kenneth I. Mavor +9 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Pakistan bears a substantial burden of hepatitis C virus (HCV) infection, with the second-highest prevalence globally. This community-based cross-sectional study, conducted from January to December 2022 in Punjab, Pakistan, investigates the ...
Raza Tirmizi +2 more
doaj +1 more source
The Evolution of Collective Action. [PDF]
A public good is produced if and only if a team of m or more volunteers contribute to it. An equilibrium-selection problem leads to the questions: will the collective action succeed? If so, who will participate in the team? The paper studies the evolution of collective action: as part of a strategy-revision process, updating players choose quantal ...
David P. Myatt, Chris Wallace
openaire +2 more sources
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The study set out to integrate collective action models and emphasize the role of emotions. Whereas the importance of anger is indisputable, relatively little attention has been paid to the role of positive emotions, such as hope, in collective action ...
Anna Wlodarczyk +3 more
doaj +1 more source
Objectives: To share a concept analysis of social movement aimed at advancing its application to evidence uptake and sustainability in health-care. Methods: We applied Walker and Avant method to clarify the concept of social movement in the context of ...
Doris Grinspun +23 more
doaj +1 more source

