Results 121 to 130 of about 1,291,148 (269)
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Why do masterplans fail? [PDF]
, 2010 Planning systems are in general addressed to make spatial projects conform to a plan, by assigning use rights in land through legally binding zoning maps and implementation rules, as it was possible to predict and impose sequences of actions and ...
Janin Rivolin, U.
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Collective action / Action collective [PDF]
Canadian Journal of Dietetic Practice and Research, 2014 openaire +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Canadian Food StudiesIn highly regulated environments such as prisons, food-related practices seem to be one of the only activities that can be controlled by incarcerated people, although this control is very limited.
Julie Courchesne, Amanda Wilson
doaj +1 more source
Public Good Provision in Indian Rural Areas: the Returns to Collective Action by Microfinance Groups [PDF]
Self-Help Groups (SHGs) are the most common form of microfinance in India. We study the impact of collective actions undertaken by these groups, composed of women only, on the variety of public goods the elected local authorities deal with.
Lore Vandewalle, Paolo Casini
core
Collective Intentionality and Individual Action [PDF]
, 2016 People often do things together and form groups in order to get things done that they cannot do alone. In short they form a collectivity of some kind or a group, for short.
Bij de Weg, Henk
core
Global Patterns of Synchronization in Human Communications
, 2017 Social media are transforming global communication and coordination. The data derived from social media can reveal patterns of human behavior at all levels and scales of society.
Bar-Yam, Yaneer +3 more
core +4 more sources