Results 81 to 90 of about 2,581,978 (278)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Adaptive Actions

open access: yes, 2009
"Adaptive Actions initiated in London in 2007 explores alterations in the workplace, the home and public spaces in general. Identifying the variety of these personal and found alterations in the city as different forms of adaptation creates a vocabulary ...
Nicolas-Le Strat, Pascal   +3 more
core   +1 more source

The Long-Awaited Directive on Representative Actions: Still Waiting for Godot…

open access: yesRevista Ítalo-Española de Derecho Procesal, 2020
On 25 November 2020, the EU adopted the Directive on Representative Actions. This long-awaited legal instrument is the first to create a binding European-wide collective action mechanism for monetary relief.
Csongor István Nagy
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Who demands collective action in an imperfect institutional environment? A case study of the profession of advocates in Russia

open access: yesJournal of Eurasian Studies, 2017
We analyse the profession of criminal defence lawyers (“advocates”) in Russia to understand their potential for collective action in an imperfect institutional environment. In 2013, we conducted a survey of 372 advocates in 9 regions of Russia.
Anton Kazun, Andrei Yakovlev
doaj   +1 more source

Collective strength, collective action [PDF]

open access: yesAmerican Journal of Infection Control, 2015
Mary Lou, Manning, Anthony D, Harris
openaire   +3 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Évolution des registres de l’action, de la ruse à la mobilisation de la notion « droit » par les habitants des bidonvilles au Maroc

open access: yesL’Année du Maghreb, 2015
Based on empirical research, this article proposes to identify the modes of protest and ranges of action used by slum dwellers to integrate their neighborhood into the city or to protest against urban transformation. Our study focuses on two slums: douar
Habiba Essahel
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Meet the Collective: Editorial Collective Bios

open access: yes, 2023
The bios of the Editorial Collective for the inaugural issue of Excessive Bodies ...
Collective , Editorial
core   +1 more source

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