Results 71 to 80 of about 2,994,625 (294)
Humanities & Social Sciences Communications, 2021 Climate change and antimicrobial resistance are two of humanity’s most imminent problems. Reducing the use of fossil fuels and antibiotics is essential for managing the threats, and theory-based policies are required to stimulate urgently needed ...
Niklas Harring, Eva M. Krockow
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Collective effects from induced behaviour
, 2000 We present a solvable model for describing quantitatively situations where the individual behaviour of agents in a group "percolates" to collective behaviour of the group as a whole as a result of mutual influence between the agents.
I.-O. Stamatescu, T. T. Wu
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The evolution of distributed sensing and collective computation in animal populations
eLife, 2015 Many animal groups exhibit rapid, coordinated collective motion. Yet, the evolutionary forces that cause such collective responses to evolve are poorly understood.
Andrew M Hein +5 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Red deer synchronise their activity with close neighbours [PDF]
, 2014 Models of collective animal behaviour frequently make assumptions about the effects of neighbours on the behaviour of focal individuals, but these assumptions are rarely tested.
Sean A. Rands +5 more
core +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Collective Household Models: Principles and Main Results. [PDF]
In the traditional approach to consumer behaviour it is assumed that households behave as if they were single decision making units. This approach has methodological, empirical and welfare economic deficiencies.
Frederic VERMEULEN
core
Methods in Ecology and EvolutionCollection of large behavioural data‐sets on wild animals in natural habitats is vital in ecology and evolution studies. Recent progress in machine learning and computer vision, combined with inexpensive microcomputers, has unlocked a new frontier of ...
Michael Chimento +3 more
doaj +1 more source