A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans
This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao +19 more
wiley +1 more source
Community music activity participation and loneliness among Chinese young adults living alone. [PDF]
Pian Y, Yu Y.
europepmc +1 more source
Charting Endocrine Progenitors Across Species and Organs
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing +21 more
wiley +1 more source
Reframing trauma-informed care for refugee and (im)migrant health systems: from interpersonal practice to structurally embedded care. [PDF]
Im H, Banu S, Koroma A, Mustafayeva S.
europepmc +1 more source
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang +11 more
wiley +1 more source
Beyond the rubble: Dengue, Chikungunya, and Vector-Borne Disease risks after 2026 Venezuela's earthquake doublet. [PDF]
Rodriguez-Morales AJ +2 more
europepmc +1 more source
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo +14 more
wiley +1 more source
Using Normalisation Process Theory to Develop a Complex Intervention: A Qualitative Case Study of Screening for Homelessness in Healthcare Settings. [PDF]
Gunatillaka N +6 more
europepmc +1 more source
Longitudinal Morphomolecular Monitoring of Head and Neck Carcinogenesis
A miniaturized endoscopic probe that integrates Raman spectroscopy and optical coherence tomography, enabling simultaneous molecular and structural imaging of living tissue, was developed. Applied longitudinally in a mouse model of head and neck cancer, the system tracks disease progression from precancerous lesions to invasive cancer.
Jianrong Qiu +7 more
wiley +1 more source
Why do Canadians host refugees? A sequential explanatory mixed-methods study protocol. [PDF]
Al-Hamad A +6 more
europepmc +1 more source

