Results 41 to 50 of about 486,108 (310)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The housing regime as a barrier to climate action

npj Climate Action
America’s current housing regime—meaning the ways housing is allocated, owned, taxed, and regulated—is a major barrier to the kinds of collective action needed to decarbonize the economy and the atmosphere.
Max Besbris, Rebecca Elliott, Daniel Aldana Cohen, Ruthy Gourevitch   +3 more
doaj   +1 more source

Housing Commons? A Scoping Review

International Journal of the Commons
The concept of commons has gained traction in housing research. However, when translated to the housing field, the notion of commons is interpreted in various ways and applied to a large range of situations.
Adrien O. T. Guisan, Tianzhu Liu, Jean-David Gerber   +2 more
doaj   +1 more source

Growing up in the new age [PDF]

, 2012
This issue of Fieldstudy was published as part of the Growing up in the New Age project. It features the archive photographs of Dave Walkling, made in a 1970s' squatted house in South London and at the Kirkdale Free School.
Dickson, Malcolm, Lippett, Zoe, Pavitt, Dean, Ryley, Marjolaine, Walkling, Dave, Williams, Val   +5 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

The Longue Durée of Housing Justice

Radical Housing Journal
This editorial frames housing justice as a question of spatial and temporal struggle, engaging the longue durée of dispossession, endurance, and collective transformation.
Aysegul Can, Melissa Fernández Arrigoitia, Saila Maria Saaristo, Andy Crosby, Melora Koepke   +4 more
doaj   +1 more source

Selected areas of intercultural relations : possible theoretical and analytical approach [PDF]

, 2017
Broadly understood intercultural relations characterizing all individual and collective interactions occur in various differentiated areas like inter alia: politics, social life, labor market, education or housing.
Banaś, Monika
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Limiting the Collective Right to Exclude [PDF]

, 2017
For decades, society’s disparate interests and priorities have stymied attempts to resolve issues of housing affordability and equity. Zoning law and servitude law, both of which have been robustly empowered by decades of jurisprudence, effectively grant
Boyack, Andrea J.
core   +2 more sources