Results 71 to 80 of about 484,816 (287)

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

O prédio de apartamentos e a moradia do operário: debates e realizações (Brasil, 1930 - 1960)

Anais do Museu Paulista: História e Cultura Material
RESUMO A partir do debate travado nas décadas de 1930 e 1940 em torno do prédio de apartamentos e de sua conveniência como moradia para trabalhadores, este trabalho discute os limites da difusão de tal tipologia no âmbito de ação de fábricas e empresas ...
TELMA DE BARROS CORREIA
doaj   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

Genossenschaftliche Prinzipien und genossenschaftliche Alltagspraxis – der gemeinschaftliche Wohnungssektor in Leipzig

Raumforschung und Raumordnung, 2017
Shortage of housing, rising real estate prices and discussions about the ‘Right to the City’ build the background to a revival of cooperative housing models in German cities.
Karin Wiest, Marie-Luise Baldin, Sophia Hildebrandt, Giulia Montanari   +3 more
doaj  

Right to adequate housing and the National Commission for the Resolution of Collective Land Conflicts of Resolution 510 of the CNJ: from the transitional regime in ADPF 828 of the STF as a permanent regime in the Judiciary

Sequência: Estudos Juridicos e Politicos
The deficit in the right to adequate housing in Brazil is an indisputable fact. Legislative policies and public policies have not proven to be sufficient and the Judiciary has acted to promote the social right to adequate housing in collective land ...
Vivian Cristina Lima López Valle, Alina Nettel Barrera, Thiago Ferrari Turra   +2 more
doaj   +1 more source

On ‘being collective’: A patchwork conversation with Somsook Boonyabancha on poverty, collective land tenure and Thailand’s Baan Mankong programme

Radical Housing Journal, 2019
Understanding rent struggles as encompassing a wide array of social relations and processes, RHJ Editors decided to include a conversation in this issue that explores collective ownership and alternative modes of land tenure.
Brenda Perez-Castro, Somsook Boonyabancha   +1 more
doaj   +1 more source

Learning to Tango: Sustainable development and the multidisciplinary dream [PDF]

, 2005
It is widely accepted that the creation of a sustainable future will require considerable collaboration between a range of academic and professional disciplines.
Bell, M
core  

Community-driven sanitation improvement in deprived urban neighbourhoods: meeting the challenges of local collective action, co-production, affordability and a trans-sectoral approach. [PDF]

, 2013
There is an international consensus that urban sanitary conditions are in great need of improvement, but sharp disagreement over how this improvement should be pursued.
McGranahan, Gordon, SHARE
core   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source