Results 71 to 80 of about 131,051 (296)

Antitrust Private Enforcement – Case of Poland [PDF]

open access: yesYearbook of Antitrust and Regulatory Studies, 2008
This article presents the main difficulties surrounding private enforcement of antitrust law in Poland, currently the key implementation problem in the field of antitrust law.
Agata Jurkowska
doaj  

Stop Firestone Student Action Kit [PDF]

open access: yes, 2007
ILRF_StudentActionKit.pdf: 235 downloads, before Oct.
International Labor Rights Forum
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

European "Class" Action: British and Italian Points of View in Evolving Scenarios [PDF]

open access: yes
The article tackles the state-of-play of the European debate with respect to the representative action as form of enhanced antitrust private enforcement. First it takes into consideration the US precedent.
Congedo, Pierluigi, Messina, Michele
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Grievance Procedures and the Democratization of American Life [PDF]

open access: yes, 1976
[Excerpt] No institution in the nation\u27s history has struggled so long and so valiantly for the democratization of American life as the organized labor movement.
Neufeld, Maurice F
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Reproduciendo diferencias: la negociación de identidades ciudadanas en el marco de la justicia transicional

open access: yesRevista de Estudios Sociales, 2017
Ever since differential rights for ethnic communities were introduced in the Colombian Constitution of 1991, there have been major disruptions and differentiations among groups that share a relationship with the land.
Carolina Angel Botero
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy