Results 41 to 50 of about 1,055,262 (297)
Robots, Autonomy, and Responsibility [PDF]
, 2016 We study whether robots can satisfy the conditions for agents fit to be held responsible in a normative sense, with a focus on autonomy and self-control.
Hakli, Raul, Mäkelä, Pekka
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Stewarding Aliveness in a Troubled Earth System
Cadmus, 2019 The state of the world suggests we are at a crossroad—the next 15 to 20 years will have a decisive impact—more than in any period before—on the conditions of life on Earth.
Petra Kuenkel, Sandra Waddock
doaj
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
A Logic for Reasoning about Group Norms [PDF]
, 2018 We present a number of modal logics to reason about group norms. As a preliminary step, we discuss the ontological status of the group to which the norms are applied, by adapting the classification made by Christian List of collective
Porello, Daniele
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
LandResearchers observed that even if one’s environmental concern was high, people would delegate others to take responsibility for climate change mitigation and undertake sustainable actions. In this study, we explored how citizens of different countries in
Anna Kwiatkowska +7 more
doaj +1 more source
Responsibility matters: putting illness back into the picture [PDF]
, 2013 Purpose – The purpose of this paper is to explore specific instances of junior doctors’ responsibility. Learning is often understood to be a prerequisite for managing responsibility and risk but this paper aims to argue that this is insufficient ...
Miriam Zukas +2 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source