Results 61 to 70 of about 1,055,262 (297)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Responsibility for implicit bias [PDF]
, 2017 Research programs in empirical psychology from the past two decades have revealed implicit biases. Although implicit processes are pervasive, unavoidable, and often useful aspects of our cognitions, they may also lead us into error.
Holroyd, Jules
core +1 more source
Cohen, Collective Responsibility, and Economic Democracy [PDF]
, 1991 My main objective in this paper is to show that Hermann Cohen\u27s ethics offers an important but hitherto neglected contribution to the- current debate within Anglo-American ethics on the moral status of the modern business ...
van der Linden, Harry
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Lea, 2017 Some events of our history hurt us deeply, as rational and moral beings, without time or recurrence of (in)direct experiences being able to create addiction. But, how can we ensure this collective memory over time?
Martina Romanelli
doaj +1 more source
Not all Humans, Radical Criticism of the Anthropocene Narrative [PDF]
, 2020 Earth scientists have declared that we are living in “the Anthropocene,” but radical critics object to the implicit attribution of responsibility for climate disruption to all of humanity. They are right to object.
Sharp, Hasana
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Transformative Listening: An Aesthetic Proposal to Justice – The 2017 NSU Tribunal in Cologne
KrisisThis article introduces transformative listening as a political and aesthetic practice of justice, developed from the 2017 NSU Tribunal in Cologne. At its center stood the survi-vors and the relatives of the victims of the racist terror of the neo-Nazi ...
Madlyn Sauer
doaj +1 more source
Solidarity and the Encapsulated and Divided Histories of Health and Human Rights
Laws, 2015 This article examines the central but neglected principle of solidarity in human rights, health and bioethics, a concept subject to contention, evasion and confusion.
Su-Ming Khoo
doaj +1 more source
Ética e integridade na ciência: da responsabilidade do cientista à responsabilidade coletiva [PDF]
, 2014 The objective of this work is to show that questions about ethics and integrity in research should be addressed from the discussion about the responsibility of the scientist and also of collective responsibility.
Russo, Marisa
core +4 more sources