Results 81 to 90 of about 1,055,262 (297)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Emerging and evolving values in the changing landscape of genomics

Frontiers in Genetics
Recent advances in human genomics have transformed the field, leading to increased integration of genomics into mainstream clinical care, broadening the potential of personalized medicine, and expanding data generation and sharing.
Maria Siermann, Maria Siermann, Riya Mohan, Eline M. Bunnik, Anne Cambon-Thomsen, Anne Cambon-Thomsen, Ruth Chadwick, Martina C. Cornel, Martina C. Cornel, Johannes J. M. van Delden, Yann Joly, Fruzsina Molnár-Gábor, Maria Pilar Nicolás Jiménez, Wim Pinxten, Emmanuelle Rial-Sebbag, Mahsa Shabani, Eva Van Steijvoort, Susan E. Wallace, Ma’n H. Zawati, Bartha Maria Knoppers, Pascal Borry   +20 more
doaj   +1 more source

Building worker power for day laborers in South Korea's construction industry [PDF]

, 2020
This article examines how unions build worker power for day laborers in South Korea’s construction industry in the context of widespread informality.
Chun, Jennifer Jihye, Yi, Sohoon
core  

Responsabilidades globales e injusticias estructurales. Una lectura de Iris Marion Youn [PDF]

, 2013
Los análisis de Iris Marion Young sobre responsabilidad política nos plantean la necesidad de pensar en las consecuencias de nuestras acciones y en cómo estas afectan a otros sujetos situados en procesos transnacionales. Este trabajo presenta una lectura
Sánchez Muñoz, Cristina
core   +3 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Responsibility of groups outside the law as a collective subject for serious human rights violations and breaches of international humanitarian law

Postulados: Revista Sociojurídica
The Colombian population has been the victim of violations of its Human Rights and breaches of International Humanitarian Law, at the hands of groups outside the law, in relation to acts of homicide, kidnapping, sexual abuse, forced displacement, among ...
Angie Paola Díaz Pérez, Thiany Stefania Ballesteros Parada   +1 more
doaj   +1 more source

Collective labor disputes and the labor inspectorate: the case of Morocco [PDF]

, 2015
The intervention of the labor inspection in the settlement of collective labor disputes is of such importance that it should be supported and approved by introducing more authority necessary and sufficient legal provision for it to good collaborate to ...
Aimad, Yaaqobi
core   +1 more source