Results 151 to 160 of about 69,052 (298)

Conceptualizing moral health for military moral injury care: theoretical foundations of the moral engagement group. [PDF]

Front Psychiatry
Antal CJ.
europepmc   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Dietitians as Food Systems Changemakers: The Path to Developing a Resilient, Equitable, Healthy and Connected Food System in the Illawarra Shoalhaven Region of Australia. [PDF]

J Hum Nutr Diet
Charlton K, Pickles S, Gebremariam AD, Stevens S, Stefoska-Needham A, Kent K.   +5 more
europepmc   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

The Concepts of Collective Security and Collective Defence in Polish Security Policy Pursued After 1918

, 2018
Celem artykułu jest prześledzenie ewolucji roli i rangi dwóch mechanizmów wielostronnych budowy bezpieczeństwa państwa, zbiorowej (kolektywnej) obrony (sojuszy wojskowych) oraz systemów bezpieczeństwa zbiorowego w polskiej polityce bezpieczeństwa w ...
Madej, Marek, Kupiecki, Robert
core  

Health Diplomacy in Africa: Prospects, Obstacles, and the Way Ahead. [PDF]

Public Health Chall
Edward M.
europepmc   +1 more source

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

Global ‘sweet enemies’ : the EU-Russia security dilemma

, 2015
This dissertation tells the story of conflict in the EU-Russia relationship. What makes this conflict definitive of a ‘security dilemma’, it is argued, is the unintended event of political violence in-between these neighbouring global powers.
Ferguson, Iain Andrew
core  

Collaborative application of the food sustainability assessment framework (FOODSAF) to transform food systems and farmer livelihoods in Makueni County, Kenya. [PDF]

PLoS One
Mukhovi SM, Ifejika Speranza C, Kiteme B, LIanque AZ.   +3 more
europepmc   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source