Results 101 to 110 of about 542,439 (287)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Enthusiast in County Medicine in the Yekaterinoslavschina-Dnipropetrovschina Region

open access: yesGastroenterologìa, 2015
There have been described life and professional activity of Petro Sochinskyi, a county physician in the Katerynoslavscyna, public activist, collector, folklorist, benefactor, acting member of Yekaterinoslavskaya Scientific Archives Committee, who made a ...
M. Chaban, Z. Shevtsova, V. Gaponov
doaj   +1 more source

Design, fabrication, testing, and delivery of a solar energy collector system for residential heating and cooling [PDF]

open access: yes
A low cost flat plate solar energy collector was designed for the heating and cooling of residential buildings. The system meets specified performance requirements, at the desired system operating levels, for a useful life of 15 to 20 years, at minimum ...
Borzoni, J. T., Holland, T. H.
core   +1 more source

Liveness-Based Garbage Collection for Lazy Languages

open access: yes, 2016
We consider the problem of reducing the memory required to run lazy first-order functional programs. Our approach is to analyze programs for liveness of heap-allocated data.
Appel A. W.   +6 more
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Indoor test for thermal performance of the GE TC-100 liquid solar collector eight- and ten-tube configuration [PDF]

open access: yes
The thermal performance of a liquid solar collector was tested in eight- and ten-tube configurations under simulated conditions. A time constant test and an incident angle modifier test were also conducted to determine the transient and incident angle ...

core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Electron beam controller [PDF]

open access: yes, 1973
An electron beam device which extracts energy from an electron beam before the electrons of the beam are captured by a collector apparatus is described.
Kosmahl, H. G.
core   +1 more source

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