Results 161 to 170 of about 542,439 (287)

A Multi-Parametric Investigation into Collector Adsorption and Its Role in the Chromite-Olivine Flotation System. [PDF]

ACS Omega
Ozun S, Raimov R.
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Challenges and needs before implementing routine pulse oximetry within primary care for sick children in West Africa: baseline assessment within the AIRE project. [PDF]

BMJ Glob Health
Hedible KGB, Anago GM, Lenaud S, Neboua D, Zair Z, Sawadogo AG, Louart S, Zombré V, Kaba DF, Sidibe A, Abarry Souleymane H, Busière S, Vignon M, Lamontagne F, Ridde V, Leroy V, AIRE Research Study Group.   +16 more
europepmc   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Care management and determinants of day 14 mortality in severely ill children aged under 5 years subsequent to hypoxaemia diagnosed using routine pulse oximetry in primary care: evidence from the AIRE project. [PDF]

BMJ Glob Health
Hedible KGB, Sawadogo AG, Zair Z, Kargougou DG, Méda B, Peters Bokol L, Kolié JS, Louart S, Ouédraogo Yugbaré S, Diakite AA, Diallo IS, Abarry Souleymane H, Busière S, Lamontagne F, Shepherd S, Ridde V, Leroy V, AIRE Research Study Group.   +17 more
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Understanding health innovation adoption: a realist evaluation of pulse oximeter implementation in primary care for children under 5 in four West African countries. [PDF]

BMJ Glob Health
Louart S, Balde H, Coulibaly A, Dagobi AE, Kadio K, Hedible KGB, Leroy V, Robert E, Ridde V, AIRE study group.   +9 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Prevalence and factors associated with severe illness in West African children under 5 years of age detected with routine pulse oximetry in primary care. [PDF]

BMJ Glob Health
Hedible KGB, Sawadogo AG, Zair Z, Kargougou DG, Agbeci H, Meda B, Peters Bokol L, Kolié J, Louart S, Ouédraogo Yugbaré S, Diakite AA, Diallo IS, Abarry Souleymane H, Neboua D, Vignon M, Busière S, Lamontagne F, Ridde V, Leroy V, AIRE Research Study Group.   +19 more
europepmc   +1 more source

Long term weathering effects on the thermal performance of the sunworks (liquid) solar collector [PDF]

The test procedures used and the results obtained during the evaluation test program of the Sunworks single-covered liquid solar collector are presented.

core   +1 more source