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A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

Colliders

open access: yes, 2020
25 pages, 19 ...
openaire   +2 more sources

Axinos in cosmology and at colliders [PDF]

open access: yesJournal of High Energy Physics, 2011
The axino, the fermionic superpartner of the axion, is a well-motivated candidate for cold dark matter if it is the lightest supersymmetric particle. Since the axino couples very weakly to the matter multiplets, the next-to-lightest supersymmetric particle (NLSP) has a long lifetime, which has important consequences for both cosmology and collider ...
Freitas, A   +3 more
openaire   +4 more sources

High-Luminosity Large Hadron Collider (HL-LHC) : Preliminary Design Report

open access: yes, 2015
The Large Hadron Collider (LHC) is one of the largest scientific instruments ever built. Since opening up a new energy frontier for exploration in 2010, it has gathered a global user community of about 7,000 scientists working in fundamental particle ...
G. Apollinari   +4 more
semanticscholar   +1 more source

Comparative Wear and Friction Analysis of Sliding Surface Materials for Hydrostatic Bearing under Oil Supply Failure Conditions

open access: yesAdvanced Engineering Materials, EarlyView.
Hydrostatic bearings excel in high‐precision applications, but their performance hinges on a continuous external supply. This study evaluates various material combinations for sliding surfaces to mitigate damage during supply failures or misalignment and to discover the most effective materials identified for enhancing the reliability and efficiency of
Michal Michalec   +6 more
wiley   +1 more source

HERA collider results [PDF]

open access: yesProceedings of XXIII International Workshop on Deep-Inelastic Scattering — PoS(DIS2015), 2016
Plenary talk at the XXIII International Workshop on Deep-Inelastic Scattering, 27th April-1st May 2015, Dallas, Texas. 14 pages, 18 figures.
openaire   +6 more sources

A very high energy hadron collider on the Moon

open access: yesNew Journal of Physics, 2022
The long-term prospect of building a hadron collider around the circumference of a great circle of the Moon is sketched. A circular collider on the Moon (CCM) of ∼11 000 km in circumference could reach a proton–proton center-of-mass collision energy of ...
James Beacham, Frank Zimmermann
doaj   +1 more source

Collider design issues based on proton-driven plasma wakefield acceleration

open access: yes, 2014
Recent simulations have shown that a high-energy proton bunch can excite strong plasma wakefields and accelerate a bunch of electrons to the energy frontier in a single stage of acceleration.
Aimidula, A.   +6 more
core   +1 more source

Additive Manufacturing of Gradient Stiffness Honeycombs Using Thermoplastic Polyurethane Composite Material Variations

open access: yesAdvanced Engineering Materials, EarlyView.
By combining porous, solid, and carbon fiber‐reinforced thermoplastic polyurethane within a single 3D printed honeycomb structure, this current work achieved precise control over spatial stiffness while ensuring strong interlayer adhesion. The findings demonstrate enhanced energy absorption and densification strain, outperforming traditional uniform ...
Savvas Koltsakidis   +2 more
wiley   +1 more source

A boosted muon collider

open access: yesJournal of High Energy Physics, 2023
Abstract A muon collider could produce the heavier Standard Model particles with a boost, for example in resonant processes such as μ−μ+→ h or μ−μ → Z. We propose machine configurations that produce the boost (asymmetric beam energies, tilted beams) and estimate how much the luminosity is reduced or perhaps enhanced.
Barducci, Daniele, Strumia, Alessandro
openaire   +3 more sources

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