Results 291 to 300 of about 231,980 (350)

Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles

open access: yesAdvanced Science, EarlyView.
The proximity labeling enzyme APEX2 is displayed on extracellular vesicle (EV) surfaces via genetic fusion with EV‐sorting scaffolds, enabling in situ biotinylation of native surface proteins, adsorbed corona components, and interacting cellular proteins.
Wenyi Zheng   +5 more
wiley   +1 more source

Pitfalls in performing genome-wide association studies on ratio traits. [PDF]

open access: yesHGG Adv
McCaw ZR   +13 more
europepmc   +1 more source

Chronic ER Stress Triggers Cell‐Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia

open access: yesAdvanced Science, EarlyView.
Acute myeloid leukemia (AML) remains a therapeutic challenge due to its heterogeneity and limited targets. Here, multi‐omics analyses are utilized, and it is revealed that AML cells, particularly the FLT3‐ITD+ subtype, undergo chaperone‐mediated ER stress, inducing surface translocation of ER chaperones.
Yimin Zhou   +13 more
wiley   +1 more source

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

open access: yesAdvanced Science, EarlyView.
ABSTRACT The cytosine (C) modifications 5‐methylcytosine (mC) and 5‐hydroxymethylcytosine (hmC) are central regulatory elements of mammalian genomes. Both marks occur in double‐stranded DNA in either strand‐symmetric or ‐asymmetric fashion, but it is still poorly understood how this symmetry information is selectively read out by the nuclear proteome ...
Lena Engelhard   +8 more
wiley   +1 more source

Low-Jitter Clock Receivers for Fast Timing Applications. [PDF]

open access: yesSensors (Basel)
Grace C   +3 more
europepmc   +1 more source

Super Time‐Resolved Tomography

open access: yesAdvanced Science, EarlyView.
A super time‐resolved tomography (STRT) approach is presented to reconstruct 4D X‐ray movies with an order‐of‐magnitude improvement in temporal resolution without sacrificing spatial resolution. By leveraging a physics‐informed deep learning algorithm that shares spatiotemporal features, STRT achieves high‐fidelity 3D reconstructions from sparse‐view ...
Zhe Hu   +6 more
wiley   +1 more source

Performance of short and long bent crystals for the TWOCRYST experiment at the Large Hadron Collider. [PDF]

open access: yesEur Phys J C Part Fields
Bandiera L   +29 more
europepmc   +1 more source

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