Bacteria Optimize Tumble Bias to Strategically Navigate Surface Constraints
The study investigates how Escherichia coli optimizes tumble bias (TB) to navigate surface constraints effectively. Using single‐cell tracking and modeling, it reveals that bacterial surface residence time decreases with increasing TB, stabilizing near the wild‐type mean TB (≈0.25), where surface diffusivity peaks.
Antai Tao+3 more
wiley +1 more source
Reply to Fitzgerald: COVID-19 vaccine mandates and voluntary vaccination behavior. [PDF]
Rains SA, Richards AS.
europepmc +1 more source
This study presents a fully automated miniature mass spectrometry system for high‐throughput therapeutic drug monitoring. Integrating magnetic solid‐phase extraction, self‐aspiration sampling miniature mass spectrometer, and U‐net deep learning quantitative algorithm, it achieves rapid (8 samples/30 min), precise (R2 > 0.99, RSD < 10%), and portable ...
Yuanhao Zhou+10 more
wiley +1 more source
With big data comes big responsibility: Strategies for utilizing aggregated, standardized, de-identified electronic health record data for research. [PDF]
Olaker VR+9 more
europepmc +1 more source
This study extensively characterizes the B cell response of rainbow trout (Oncorhynchus mykiss) in response to red mark syndrome (RMS). This disease, suspected to be caused by a Midichloria‐like organism (MLO), induces skin lesions in the infected animals, characterized by a massive influx of IgM+ B cells.
J Germán Herranz‐Jusdado+10 more
wiley +1 more source
Directed acyclic graphs to minimise bias and optimise causal inference in SNAP-3: an observational cohort study of frailty, multimorbidity, and delirium in older surgical patients. [PDF]
Swarbrick CJ+4 more
europepmc +1 more source
This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen+9 more
wiley +1 more source
Potential biases in test-negative design studies of COVID-19 vaccine effectiveness arising from the inclusion of asymptomatic individuals. [PDF]
Ortiz-Brizuela E+5 more
europepmc +1 more source
Proton Acceleration with Relativistic Electromagnetic Shock
New Ion Acceleration Mechanism! A novel cosmic‐ray proton acceleration mechanism is proposed, where relativistic electromagnetic shocks accelerate protons transversely. Hamiltonian analysis yields a scaling law linking the proton energy to the minimum longitudinal thickness of the shock.
Ting Xiao+5 more
wiley +1 more source
US states that mandated COVID-19 vaccination see higher, not lower, take-up of COVID-19 boosters and flu vaccines. [PDF]
Fitzgerald J.
europepmc +1 more source