Results 311 to 320 of about 350,893 (372)

Nanoscale Metal‐Organic Framework‐Based Self‐Monitoring Oxygen Economizer and ROS Amplifier for Enhanced Radiotherapy‐Radiodynamic Therapy

Advanced Science, EarlyView.
A Fe (III)–Pt (II) porphyrin framework‐based radiosensitizer (FPTM‐LP) is constructed to serve as an oxygen economizer, hypoxia self‐monitoring device, and reactive oxygen species (ROS) amplifier. The glutathione (GSH)/pH‐responsive release of lonidamine achieves oxygen‐economization to combat hypoxia‐induced radioresistance guided by near infrared ...
Shiye Du, Qiang Wen, Ting Han, Jiongyu Ren, Mingyu Wang, Yunpeng Dai, Xiaoguang Ge, Lu Li, Junzhi Liu, Shi Gao   +9 more
wiley   +1 more source

An automated bandwidth division for the LHCb upgrade trigger. [PDF]

Comput Softw Big Sci
Evans T, Fitzpatrick C, Fitzpatrick C, Horswill J.   +3 more
europepmc   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Decomposing causality into its synergistic, unique, and redundant components. [PDF]

Nat Commun
Martínez-Sánchez Á, Arranz G, Lozano-Durán A.   +2 more
europepmc   +1 more source

Dual‐Band Electrochromic Smart Window for Dynamic Switching Between Radiative Cooling and Solar Heating

Advanced Science, EarlyView.
In this study, an electrochromic glass is designed by effectively integrating silver electrodeposition with mechanical flipping of the glass panel, enabling bidirectional dynamic regulation of the solar and mid‐infrared spectra. Its capability to dynamically switch between radiative cooling and solar heating modes offers substantial energy‐saving ...
Xinyu Zhao, Qixiang Chen, Fan Fan, Qiliang Wang, Yuehong Su, Minsu Liu, Fahua Zhu, Dongliang Zhao   +7 more
wiley   +1 more source

Comparison of random forest methods for conditional average treatment effect estimation with a continuous treatment. [PDF]

Stat Methods Med Res
Tabib S, Larocque D.
europepmc   +1 more source

O‐GalNAc Glycosylation Activates MBL‐Mediated Complement and Coagulation Cascades to Drive Organotropic Metastasis

Advanced Science, EarlyView.
Upregulated glycosyltransferase GALNT9 in neuroendocrine (NE) carcinomas increases O‐GalNAc glycosylation on cell membrane proteins, particularly Annexin‐A2 (ANXA2). Elevated O‐GalNAc glycan induces the binding of NE cancer cells to mannose binding lectin 2 (MBL2), activating the MBL‐MBL associated serine protease (MBL‐MASP) complement pathway in the ...
Xinyu Chen, Wei Bao, Kaiyuan Liu, Na Jing, Genyu Du, Luyao Jiang, Qian You, Yingchao Zhang, Penghui Xu, Chaping Cheng, Nan Wang, Xialian Xi, Mingyue Wang, Yiyun Liu, Jinming Wang, Huifang Zhao, Shilei Zhang, Dinglan Wu, Chi‐Fai Ng, Jiahua Pan, Wei Xue, Wei‐Qiang Gao, Pengcheng Zhang, Kai Zhang, Helen He Zhu   +24 more
wiley   +1 more source

Rethinking animal attrition in preclinical research: Expressing causal mechanisms of selection bias using directed acyclic graphs. [PDF]

J Cereb Blood Flow Metab
Collazo A, Kuhn HG, Kurth T, Piccininni M, Rohmann JL.   +4 more
europepmc   +1 more source

Genetic Impacts on the Structure and Mechanics of Cellulose Made by Bacteria

Advanced Science, EarlyView.
A genetic mutation in a protease of a cellulose‐overproducing evolved bacterium significantly affects the proteome, structure, and mechanical properties of bio‐fabricated cellulose pellicles. By overexpressing synthase proteins that build the cellulose‐forming biological machinery of the cell, the evolved bacterium generates dense, stiff, and strong ...
Julie M. Laurent, Mathias Steinacher, Anton Kan, Maximilian Ritter, Mario Leutert, Siiri Bienz, David Häberlin, Naresh Kumar, André R. Studart   +8 more
wiley   +1 more source