Results 341 to 350 of about 356,721 (378)

Periodontitis and atherosclerotic cardiovascular disease. [PDF]

Mol Cells
Kim JY, Lee K, Lee MG, Kim SJ.
europepmc   +1 more source

Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice

Advanced Science, EarlyView.
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia, Xiaoyuan Jing, Ruoxi Wang, Mengke Su, Pei Wang, Yingxin Feng, Xiaohu Ren, Longfang Tu, Ping Wei, Zhen Lu, Yicong Jia, Feng Hong, Zhizhun Mo, Jiemeng Zou, Kang Huang, Caiyun Yan, Qianhui Zou, Liang Wang, Guoping Zhong, Zhi Zeng, Qiuliyang Yu, Wen Su, Xifei Yang, Fan Pan, Jianzhi Wang, Liping Wang, Lijun Kang, Paul J. Kenny, Zuxin Chen, Xin‐an Liu   +29 more
wiley   +1 more source

Skullcapflavone II Inhibits SLC1A4‐Mediated L‐Serine Uptake and Promotes Mitochondrial Damage in Gastric Cancer

Advanced Science, EarlyView.
Skullcapflavone II (SkII) significantly alters serine metabolism in gastric cancer cells by directly targeting the L‐serine transporter SLC1A4, thereby inhibiting L‐serine uptake rather than de novo synthesis. This disruption of serine metabolism by SkII leads to increased oxidative stress and consequent mitochondrial damage.
Jing Zhao, Yu‐Bo Ma, Rui‐Hong Xia, Zheng‐Chen Jiang, Ying Zhou, Ya‐Nan Wang, Meng‐Yan Yang, Jing‐Jie Dai, Tao Zhu, Li‐Bin Pan, Li Yuan   +10 more
wiley   +1 more source

Estimating Causal Effects on a Disease Progression Trait Using Bivariate Mendelian Randomisation. [PDF]

Genet Epidemiol
Cai S, Dudbridge F.
europepmc   +1 more source

Targeting a hypothetical estimand based on adherence with the parametric g-formula: A post hoc secondary analysis of the MET-PREVENT randomised controlled trial

Hiu S, Wilson N, Wilson K, Lin N, Witham MD, Wason J.   +5 more
europepmc   +2 more sources

Reply to Fitzgerald: COVID-19 vaccine mandates and voluntary vaccination behavior. [PDF]

Proc Natl Acad Sci U S A
Rains SA, Richards AS.
europepmc   +1 more source

Search for additional scalar bosons within the Inert Doublet Model in a final state with two leptons at the FCC-ee. [PDF]

Eur Phys J C Part Fields
Bal A, Curtis E, Magnan AM, Maier B, Robens T, Wardle N.   +5 more
europepmc   +1 more source

US states that mandated COVID-19 vaccination see higher, not lower, take-up of COVID-19 boosters and flu vaccines. [PDF]

Proc Natl Acad Sci U S A
Fitzgerald J.
europepmc   +1 more source

With big data comes big responsibility: Strategies for utilizing aggregated, standardized, de-identified electronic health record data for research. [PDF]

Clin Transl Sci
Olaker VR, Fry S, Terebuh P, Davis PB, Tisch DJ, Xu R, Miller MG, Dorney I, Palchuk MB, Kaelber DC.   +9 more
europepmc   +1 more source

Stochastic treatment regimes in climate-health research: Reassessing malaria risk under warming scenarios in Colombia. [PDF]

PLOS Glob Public Health
Gutiérrez JD.
europepmc   +1 more source