Results 81 to 90 of about 348,407 (331)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Optimization of Cation Exchange for the Separation of Actinium-225 from Radioactive Thorium, Radium-223 and Other Metals

Molecules, 2019
Actinium-225 (225Ac) can be produced with a linear accelerator by proton irradiation of a thorium (Th) target, but the Th also underdoes fission and produces 400 other radioisotopes.
Jonathan Fitzsimmons, Bryan Foley, Bryna Torre, Megan Wilken, Cathy S. Cutler, Leonard Mausner, Dmitri Medvedev   +6 more
doaj   +1 more source

DIS Prospects at the Future Muon Collider Facility [PDF]

, 1998
We discuss prospects of deep inelastic scattering physics capabilities at the future muon collider facility. In addition to mu^+ mu^- collider itself, the facility provides other possibilities. Among the possibilities, we present muon-proton collider and
Yu, J.
core   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Physics at Future Colliders [PDF]

, 1997
After a brief review of the Big Issues in particle physics, we discuss the contributions to resolving that could be made by various planned and proposed future colliders.
Ellis, John
core   +1 more source

Physics Opportunities of e+e- Linear Colliders [PDF]

, 1996
We describe the anticipated experimental program of an e+e- linear collider in the energy range 500 GeV -- 1.5 TeV. We begin with a description of current collider designs and the expected experimental environment.
Anderson GW, Appelquist T, Appelquist T, Arnold P, Atwood D, Baer H, Baer H, Bar-Shalom S, Bardeen WA, Barger V, Barger V, Barger V, Barnett RM, Bartel W, Bigi I, Borden DL, Borden DL, Boudjema F, Brodsky SJ, Bèlanger G, Chen P, Cornwall JM, Dawson S, Del Aguila F, Dimopoulos S, Djouadi A, Djouadi A, Djouadi A, Doncheski MA, Eboli OJP, Fadin VS, Feigenbaum J, Feng JL, Feng JL, Fujii K, Ginzburg IF, Gray N, Gunion JF, Gunion JF, Gunion JF, Hagiwara K, Heusch CA, Hildreth MD, Hitoshi Murayama, Holdom B, Iddir F, Jezabek M, Jezabek M, Kane GL, Kane GL, Keung WY, Kramer M, Kwong W, Kühn JH, Ladinsky GA, Lane K, Langacker P, Langacker P, Manohar A, Michael E. Peskin, Murayama H, Nadeau H, Nojiri MM, Strassler MJ, Sumino Y, Susskind L, Tandean J, Tsukamoto T, Weinberg S, Weinberg S, Yehudai E, Yehudai E, Yuan CP, Yuan CP   +73 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Review of IoT Systems for Air Quality Measurements Based on LTE/4G and LoRa Communications

IoT
The issue of air pollution has recently come to light due to rapid urbanization and population growth globally. Due to its impact on human health, such as causing lung and heart diseases, air quality monitoring is one of the main concerns.
Mpho Gift Doctor Gololo, Clinton Wenfrey Nyathi, Lennox Boateng, Edward Khomotso Nkadimeng, Ryan Peter Mckenzie, Iqra Atif, Jude Kong, Muhammad Ahsan Mahboob, Ling Cheng, Bruce Mellado   +9 more
doaj   +1 more source

A Quality Control Assay to Access the HCl Molarity of Radionuclide Solutions

Chemosensors, 2016
Strontium-82 is produced by proton activation of a rubidium chloride target in an accelerator or cyclotron and purified by ion exchange chromatography. The Strontrium-82 is used in Cardigen generators to produce Rubidium-82 for cardiac imaging.
Jonathan Fitzsimmons
doaj   +1 more source

Anatomy of inclusive tt‾W production at hadron colliders

Physics Letters B, 2020
In LHC searches for new and rare phenomena the top-associated channel pp→tt‾W±+X is a challenging background that multilepton analyses must overcome. Motivated by sustained measurements of enhanced rates of same-sign and multi-lepton final states, we ...
Stefan von Buddenbrock, Richard Ruiz, Bruce Mellado   +2 more
doaj   +1 more source