First reported case of triple benign ovarian collision tumor of the left ovary mimicking malignancy on ultrasound and CT imaging: sclerosing stromal tumor, serous cystadenoma, and fibroma. [PDF]
Alwaraa E +4 more
europepmc +1 more source
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source
Bio-Inspired Metaheuristics for Time-Optimal Trajectory Planning in Cooperative Dual-Arm Bimanipulation. [PDF]
Peñacoba-Yagüe M +2 more
europepmc +1 more source
An integrated approach combining mass spectrometry imaging, transcriptomics, and phylogenetic analysis facilitated the efficient identification of genes involved in gallotannin biosynthesis in Paeonia suffruticosa. As a result, a key UGT and several SCPL acyltransferases responsible for biosynthesizing pentagalloylglucose were successfully identified ...
Yushi Liu +4 more
wiley +1 more source
Policy-Guided Model Predictive Path Integral for Safe Manipulator Trajectory Planning. [PDF]
Liang L, Wu C, Wang X.
europepmc +1 more source
KDM4A Erases the H3R17me2a Mark, Facilitating Chromosome Condensation
This study reveals a reversible histone modification switch governing chromosome condensation during mitosis. PKCα‐activated KDM4A removes H3R17me2a, permitting Suv39h1‐driven H3K9me3 deposition. This epigenetic transition recruits the chromosomal passenger complex and triggers Aurora B‐dependent H3S10 phosphorylation, coordinating chromatin remodeling
Yena Cho +6 more
wiley +1 more source
Clinical and kinematic responses to neck injuries in low-speed reverse motor vehicle collision tests: a human volunteer study. [PDF]
Lee HY +10 more
europepmc +1 more source
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He +10 more
wiley +1 more source
A multimodal approach for assessing the risk of cervical spine injury in low-speed rear-end collisions: kinematic and clinical responses. [PDF]
Lee HY +7 more
europepmc +1 more source
Ultrasound Modulation of Visual Circuits in Mice Independent of Auditory Confound
In this study, Qiu et al. found that low‐intensity ultrasound can directly activate sparse ultrasound‐sensitive neurons (UNs) in the primary visual cortex (V1) of deafened mice. The proportion of these sparse UNs is pressure‐dependent. Furthermore, ultrasound modulates visual circuitry with distinct excitatory and inhibitory effects.
Jiaru He +8 more
wiley +1 more source

