Results 161 to 170 of about 204,726 (218)
Charge‐Transfer‐Mediated Boron Magneto‐Ionics: Towards Voltage‐Driven Multi‐Ion Transport
Advanced Science, EarlyView.This study demonstrates voltage‐driven multi‐ion transport in FeBO systems, revealing simultaneous motion of B, Fe, and O ions enabled by charge‐transfer effects. By tuning oxidation states through oxygen incorporation, we achieve a transition from electrostatic‐like to electrochemical magneto‐ionic behavior. The findings establish boron magneto‐ionics,
Zheng Ma +15 more
wiley +1 more source
Emergent Spinning and Orbital Motion in Clustered Wind‐Assisted Flyers
Advanced Science, EarlyView.Inspired by natural snowflake geometries, paper‐cut flyers exhibit geometry‐defined spinning and orbital motions during cluster formation in a wind tunnel. Collective flights of multiple paperflakes reveal dynamic clustering, fragmentation, and continuously evolving spin behaviors.
Bingnan Zhou +7 more
wiley +1 more source
Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform
Advanced Science, EarlyView.Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao +10 more
wiley +1 more source
A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43
Advanced Science, EarlyView.Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg +16 more
wiley +1 more source
Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Advanced Science, EarlyView.As displayed in Graphical Abstract image.tif, a molecular‐design strategy precisely tailors high‐speed droplet dynamics through programmed surfactant co‐assembly. The structural transition into an entangled wormlike micelle network completely suppresses stochastic splashing on fibrous substrates.
Shuling Liu +6 more
wiley +1 more source
MMR deficient dedifferentiated endometrial carcinoma with synchronous uterine leiomyosarcoma: a rare collision tumour-case report and literature review. [PDF]
Oxf Med Case ReportsSaeed MS +4 more
europepmc +1 more source
A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers
Advanced Science, EarlyView.Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels +2 more
wiley +1 more source
Incident Risk Prediction for Global Maritime Networks Under a Changing Climate. [PDF]
Risk AnalAzadnia A, Miller-Hooks E.
europepmc +1 more source
Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance
Advanced Science, EarlyView.Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer +9 more
wiley +1 more source