Results 191 to 200 of about 1,420,902 (265)

RFWD3 Reprograms Nucleotide Metabolism Through PHGDH to Induce Chemoresistance In Osteosarcoma

Advanced Science, EarlyView.
RFWD3 is identified as a key regulator of cisplatin (DDP) sensitivity in osteosarcoma using a genome‐wide CRISPR screen. RFWD3 promotes PHGDH ubiquitination, enhancing NAD+‐mediated nucleotide biosynthesis. Knocking out RFWD3 sensitized osteosarcoma cells to DDP.
Wenchao Zhang, Chi Yin, Lin Qi, Zhongyue Liu, Ruiling Xu, Chao Tu, Zhihong Li   +6 more
wiley   +1 more source

Time-Interval-Based Collision Detection for 4WIS Mobile Robots in Human-Shared Indoor Environments. [PDF]

Sensors (Basel)
Kim S, Jang H, Ha J, Lee D, Ha Y, Song Y.   +5 more
europepmc   +1 more source

TRAF3IP3 Induces ER Stress‐Mediated Apoptosis with Protective Autophagy to Inhibit Lung Adenocarcinoma Proliferation

Advanced Science, EarlyView.
Schematic diagram of the working model of TRAF3IP3 in the coordination of ER stress and autophagy related apoptosis in lung cancer cells. Abstract TNF receptor‐associated factor 3 interacting protein 3 (TRAF3IP3/T3JAM) exhibits dual roles in cancer progression. While upregulated in most malignancies and critical for immune regulation.
Guang Zhao, Jun Qi, Fang Li, Haotian Ma, Rui Wang, Xiuyi Yu, Yufei Wang, Sida Qin, Jie Wu, Chen Huang, Hong Ren, Boxiang Zhang   +11 more
wiley   +1 more source

Anionic Reactions Degrading SF₆ Using Metals: Insights From the Gas Phase. [PDF]

Rapid Commun Mass Spectrom
Joshi S, Barden S, Mayer PM.
europepmc   +1 more source

Data‐Driven Theoretical Modeling of Centrifugal Step Emulsification and Its Application in Comprehensive Multiscale Analysis

Advanced Science, EarlyView.
A customized assembled centrifugal step emulsifier is utilized to generate an end‐point experimental dataset for droplet generation. By integrating real‐time numerical simulations, a predictive model for droplet generation is developed, meeting the diverse droplet size requirements necessary for bioassays involving molecules, bacteria, and cells ...
Xin Wang, Xiaolu Cai, Chao Wan, Huijuan Yuan, Shunji Li, Yiwei Zhang, Ran Zhao, Yuxi Qin, Yiwei Li, Bi‐Feng Liu, Peng Chen   +10 more
wiley   +1 more source

Collision detection method for anchor digging machine water drilling rig. [PDF]

Sci Rep
Liu ZX, Yan ST, Zou K, Xie M.
europepmc   +1 more source

NAD+ Metabolism Reprogramming Drives SIRT1‐Dependent Deacetylation Inducing PD‐L1 Nuclear Localization in Cervical Cancer

Advanced Science, EarlyView.
The identification of PD‐L1 localization may be a key factor in the resistance to immunotherapy observed in patients. The discovery that PD‐L1 over expression is regulated by both transcriptional and post‐transcriptional processes. The acetyl‐proteomic analysis that identified SIRT1 as a key player in the deacetylation of histone H3 at lysines 27 and ...
Xinyi Lu, Pingping Jin, Qianyun Tang, Min Zhou, Hanjie Xu, Chen Su, Lei Wang, Feng Xu, Min Zhao, Yongxiang Yin, Jinqiu Zhang, Zhen Jia, Xinrui Peng, Jie Zhou, Lu Wang, Yan Chen, Min Wang, Min Yang, Daozhen Chen, Yu Chen   +19 more
wiley   +1 more source

Evaluation of advanced emergency braking systems in drowsy driving-related real-world truck collisions. [PDF]

Sleep
Kawaguchi K, Kumagai H, Sawatari H, Yokoyama M, Kiyohara Y, Hayashi M, Shiomi T.   +6 more
europepmc   +1 more source

Genome‐Wide Association Studies Reveal the Genetic Architecture of Ionomic Variation in Grains of Tartary Buckwheat

Advanced Science, EarlyView.
In this study, variation and genetic basis of ionome among Tartary buckwheat population are investigated, illuminating their significance in the domestication and diversification of Tartary buckwheat. And three genes (FtACA13 for Na content, FtYPQ1 for Zn content, FtNHX2 for As content) are identified with the dominant haplotypes and functional ...
Zhirong Wang, Yuqi He, Mengyu Zhao, Xiang‐Qian Liu, Hao Lin, Yaliang Shi, Kaixuan Zhang, Guijie Lei, Dili Lai, Tong Liu, Xiaoyang Peng, Jiayue He, Wei Li, Xiangru Wang, Sun‐Hee Woo, Muriel Quinet, Alisdair R. Fernie, Xin‐Yuan Huang, Meiliang Zhou   +18 more
wiley   +1 more source

Characterization of the Microstructure and Interfacial Morphology of Magnetic Pulse Welded Steel/Al Tubes. [PDF]

Materials (Basel)
Hu T, Li B, Wu T, Pan H, Ding K, Gao Y.
europepmc   +1 more source