AKT1 Phosphorylates FDX1 to Promote Cuproptosis Resistance in Triple‐Negative Breast Cancer
This study demonstrates that copper activates the AKT signaling pathway, which inhibits ferredoxin‐1 (FDX1), a key regulator of cuproptosis. AKT1‐mediated FDX1 phosphorylation not only abrogates FDX1‐induced cuproptosis and aerobic respiration but also promotes glycolysis.
Zicheng Sun+10 more
wiley +1 more source
Optimisation of Heated Electrospray Ionisation Parameters to Minimise In-Source Generated Impurities in the Analysis of Oligonucleotide Therapeutics. [PDF]
Glenister MA+4 more
europepmc +1 more source
Advancements in Biochar as a Sustainable Adsorbent for Water Pollution Mitigation
Biochar, obtained through pyrolysis of organic waste, serves as a sustainable solution for wastewater treatment due to its adaptability and low‐cost nature. This review comprehensively examines recent advancements in biochar production, functional modifications, and applications, highlighting the integration of machine learning and artificial ...
Devika Laishram+3 more
wiley +1 more source
Enhancing Maritime Safety: Estimating Collision Probabilities with Trajectory Prediction Boundaries Using Deep Learning Models. [PDF]
Jurkus R+3 more
europepmc +1 more source
Schematic diagram of the working model of TRAF3IP3 in the coordination of ER stress and autophagy related apoptosis in lung cancer cells. Abstract TNF receptor‐associated factor 3 interacting protein 3 (TRAF3IP3/T3JAM) exhibits dual roles in cancer progression. While upregulated in most malignancies and critical for immune regulation.
Guang Zhao+11 more
wiley +1 more source
Collision tumor in the thyroid gland, "even with" Hashimoto's thyroiditis: a double-edged sword in thyroidology? [PDF]
Cinar I, Sengul I.
europepmc +1 more source
In this study, variation and genetic basis of ionome among Tartary buckwheat population are investigated, illuminating their significance in the domestication and diversification of Tartary buckwheat. And three genes (FtACA13 for Na content, FtYPQ1 for Zn content, FtNHX2 for As content) are identified with the dominant haplotypes and functional ...
Zhirong Wang+18 more
wiley +1 more source
Nonlinearities investigation and experimental validation insights into mechanical model of yoke-type inerter for enhanced vibration suppression. [PDF]
Zhang R, Tao Q, Zhang L, Hao L, Xue S.
europepmc +1 more source
The chemical reaction of carbon monoxide and hydrogen after collision with electrons
A. Caress, Eric Keightley Rideal
openalex +1 more source