Results 231 to 240 of about 28,522,762 (408)
A Legendre Spectral Collocation Method for the Biharmonic Dirichlet Problem [PDF]
Bernard Bialecki, Andréas Karageorghis
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Mechanisms of enhancer‐driven oncogene activation
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend+2 more
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Enhancer‐dependent gene regulation in space, time, and malignancies
Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum+2 more
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Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert+3 more
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Abstract Divergent thinking (DT) is an important constituent of creativity that captures aspects of fluency and originality. The literature lacks multivariate studies that report relationships between DT and its aspects with relevant covariates, such as cognitive abilities, personality traits (e.g. openness), and insight. In two multivariate studies (N
S. Weiss+6 more
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This paper is focused on computing an approximate numerical solution of the strongly nonlinear multi-order fractional version (SNMOFV) of a BVP that appears in the theory of chemical reactors.
Devendra Kumar+2 more
doaj
Jacobi spectral collocation method for the approximate solution of multidimensional nonlinear Volterra integral equation. [PDF]
Wei Y, Chen Y, Shi X, Zhang Y.
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Abstract This research investigates the interplay between sustainable finance, energy policies, and environmental outcomes in OECD countries from 2005 to 2018. Recognising the pivotal role of OECD countries in global sustainability efforts, this study focuses on Australia, Belgium, Denmark, Germany, Japan, Norway, Portugal, Spain, Sweden, and ...
Bilgehan Tekin+2 more
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The Discretization of Neutral Functional Integro-Differential Equations by Collocation Methods
Hermann Brunner
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