Results 41 to 50 of about 67,435 (287)

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Does ursodeoxycholic acid change the proliferation of the colorectal mucosa? A randomized, placebo-controlled study [PDF]

, 2003
Background: In animal models ursodeoxycholic acid (UDCA) showed a chemoprotective effect against colon cancer. To explain this, a reduced proliferation of the colorectal mucosal proliferation was suggested.
Diebold, J., Göke, B., Hay, U., Marsteller, I., Ochsenkühn, Thomas, Paumgartner, Gustav, Sackmann, M.   +6 more
core   +1 more source

In Vivo CRISPR Screening Identifies the Glutamate Receptor GRIA2 as Promoting Peritoneal Metastasis of Gastric Cancer via Calcium‐Dependent β‐Catenin Activation

Advanced Science, EarlyView.
We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun, Xu Yang, Wenchao Jiang, Chengbo Ji, Yingying Wu, Haoyu Sun, Xinyou Liu, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Junjie Zhao, Yuanyuan Ruan, Haojie Li, Xuefei Wang   +13 more
wiley   +1 more source

Necrotizing fasciitis of the thigh due to penetrated descending colon cancer: a case report

Surgical Case Reports, 2018
Background Necrotizing fasciitis (NF) caused by colorectal cancer is rare, and very few cases associated with colon cancer have been reported. We describe the case of a patient with NF in the left thigh due to penetration of descending colon cancer who ...
Kentaro Sato, Hitoshi Yamamura, Yoshiyuki Sakamoto, Hajime Morohashi, Takuya Miura, Toru Yoshikawa, Akiko Suto, Satoru Tsuruta, Kenichi Hakamada   +8 more
doaj   +1 more source

Comparative study of descendent colon rupture resistance considering traction force of rupture and total energy of rupture in rats [PDF]

Acta Cirúrgica Brasileira, 2006
PURPOSE: To compare total energy of rupture and traction force of rupture tests within a rupture resistance study of descendent colon of rats. METHODS: Twelve descendent colon segments of rats were considered to perform the study.
Feng Chung Wu, Huei Diana Lee, Maksoel Algustin Krauspenhar Niz, Maria de Loudes Setsuko Ayrizono, Cláudio Saddy Rodrigues Coy, Juvenal Ricardo Navarro Góes, João José Fagundes   +6 more
doaj   +1 more source

Metastasis of Ovarian Cancer to the Descending Colon

Case Reports in Gastroenterology, 2023
Colonic metastasis from ovarian cancer is extremely rare, with only seven reported cases. A 77-year-old woman who had previously undergone surgery for ovarian cancer was admitted to a local hospital with anal bleeding.
Kentaro Abe, Hiroyuki Anzai, Satoko Eguchi, Masako Ikemura, Aya Shinozaki-Ushiku, Takahide Shinagawa, Hirofumi Sonoda, Yuichiro Yoshioka, Yuzo Nagai, Shinya Abe, Hiroyuki Matsuzaki, Yuichiro Yokoyama, Shigenobu Emoto, Koji Murono, Kazuhito Sasaki, Hiroaki Nozawa, Tetsuo Ushiku, Soichiro Ishihara   +17 more
doaj   +1 more source

EFSUMB Recommendations and Guidelines for Gastrointestinal Ultrasound - Part 1: Examination Techniques and Normal Findings (Long version). [PDF]

, 2016
▼ In October 2014 the European Federation of Societies for Ultrasound in Medicine and Biology formed a Gastrointestinal Ultrasound (GIUS) task force group to promote the use of GIUS in a clinical setting.
Calabrese, E., Dietrich, C. F., Dirks, K., Gilja, O. H., Hausken, T., Higginson, A., Hollerweger, A., Maaser, C., Maconi, G., Nuernberg, D., Nylund, K., Pallotta, Nadia, Ripolles, T., Romanini, L., Saftoiu, A., Serra, C., Sporea, I.   +16 more
core   +3 more sources

Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol‐Induced Intestinal Injury via Microbiota‐Dependent and ‐Independent AHR Activation

Advanced Science, EarlyView.
Glucuronolactone (GLU) as a natural metabolite of glucose, increases Lactobacillus amylovorus abundance and luminal IAA level to activate AHR signaling. In addition, GLU itself can directly elevate AHR signaling activity independently of microbiota and IAA.
Chenbin Cui, Beibei Zhang, Jiaxi Tang, Jing Hou, Yueqin Qiu, Kaiguo Gao, Li Wang, Zongyong Jiang, Xuefen Yang   +8 more
wiley   +1 more source

The pattern of lymph node metastasis and the outcome of high and low dissection in descending colon cancer

Asian Journal of Surgery
Background/objectives: Few studies focused on the distribution of lymph node metastasis and outcomes of different dissection levels in descending colon cancer.
Yu-Zu Lin, Yi-Wen Yang, Che-Yuan Chang, Hou-Hsuan Cheng, Sheng-Chieh Huang, Hung-Hsin Lin, Chun-Chi Lin, Yuan-Tzu Lan, Huann-Sheng Wang, Shung-Haur Yang, Jeng-Kai Jiang, Shih-Ching Chang   +11 more
doaj   +1 more source

Spontaneous descending colon hematoma due to a rare complication of warfarin therapy: A case report

Clinical Case Reports, 2021
Intramural hematoma of the colon should be considered as a diagnosis in anticoagulated patients who present with prolonged INR and GI symptoms. In stable cases, conservative medical treatment can be sufficient to avoid unnecessary procedures.
Negin Yavari, Farzaneh Majdi Nassab, Mohammad Amin Tajvidi, Shapour Shirani, Shahram Shirani, Seyed Hossein Ahmadi Tafti   +5 more
doaj   +1 more source