Results 71 to 80 of about 47,148 (235)

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

Label Noise in Pathological Segmentation Is Overlooked, Leading to Potential Overestimation of Artificial Intelligence

Cancer Science, EarlyView.
This study evaluated how artificial label noise affects cancer pathology segmentation models, demonstrating that boundary‐dependent noise leads to overestimation of performance metrics, while random noise mixtures further harm generalization. Our results highlight the need for standardized noise‐quantification and mitigation methods and for developing ...
Kenji Harada, Yuichiro Nomura, Daisuke Komura, Shumpei Ishikawa, Shingo Sakashita   +4 more
wiley   +1 more source

Asymptomatic sigmoid diverticulum perforation-induced subcutaneous, mediastinal, and retroperitoneal emphysema: A case report and literature review

Respiratory Medicine Case Reports
Background: Mediastinal and subcutaneous emphysema usually result from spontaneous rupture of the alveolar wall. We present an educational case of subcutaneous, mediastinal, and retroperitoneal emphysema discovered during a routine medical check-up ...
Daichi Setoguchi, Naoki Iwanaga, Kotaro Nema, Tomoya Hagiwara, Kotaro Hayashida, Koki Yamashita, Tatsuro Hirayama, Masataka Yoshida, Kazuaki Takeda, Shotaro Ide, Masato Tashiro, Takahiro Takazono, Masachika Kitajima, Noriho Sakamoto, Koichi Izumikawa, Katsunori Yanagihara, Keiji Inoue, Hiroshi Mukae   +17 more
doaj   +1 more source

Dietary anthocyanidin pelargonidin activates G protein‐coupled receptor 35

The FEBS Journal, EarlyView.
Pelargonidin, a red‐fruit‐derived anthocyanidin, was newly identified as a dietary agonist of GPR35, a metabolite‐sensing GPCR implicated in anti‐inflammation. Through screening of dietary compounds, pelargonidin emerged as a potent GPR35 agonist, attenuating inflammation in human intestinal cells.
Fumie Nakashima, Sayako Shimomura, Mayuka Wakabayashi, Wei Qi Loh, Harumi Ando, Haruka Sei, Hiroyuki Hattori, Didik Huswo Utomo, Masaki Kita, Asuka Inoue, Koji Uchida, Takahiro Shibata   +11 more
wiley   +1 more source

Sigmoid and cecum colon volvulus: a case report

Journal of Medical Case Reports
Introduction Colon volvulus is the twisting of a segment of colon on its mesenteric axis, which can lead to the obstruction of the lumen and the blood supply.
Dilawer Chofan Charo, Fares Medhat Mohammad, Mahmoud Issam Ghmera, Batoul Aksam Saker, Ayman Ali Ghosnah   +4 more
doaj   +1 more source

Giant Sigmoid Colon Diverticulum [PDF]

Digestive Surgery, 2007
José, Salazar-Ibargüen, Ricardo O, Escárcega, Gonzalo, Pérez Chávez   +2 more
openaire   +2 more sources

Brain tissue classification in hyperspectral images using multistage diffusion features and transformer

Journal of Microscopy, EarlyView.
Abstract Brain surgery is a widely practised and effective treatment for brain tumours, but accurately identifying and classifying tumour boundaries is crucial to maximise resection and avoid neurological complications. This precision in classification is essential for guiding surgical decisions and subsequent treatment planning.
Neetu Sigger, Tuan T. Nguyen, Gianluca Tozzi   +2 more
wiley   +1 more source

Synchronic Volvulus of Sigmoid and Transverse Colon: A Rare Case of Large Bowel Obstruction [PDF]

Iranian Journal of Colorectal Research, 2014
Introduction: Volvulus of two segments of colon has been reported rarely, as either synchronous or metachronous events. Colonic volvulus involving both transverse and sigmoid colon is a rare medical problem frequently dismissed as a cause of large bowel ...
Alireza Hoseini, Reza Eshragi Samani, Hamed Parsamoin, Hamidreza Jafari   +3 more
doaj  

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, EarlyView.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Use of Laxative-Augmented Contrast Medium Increases the Accuracy in the Detection of Colorectal Neoplasms

Diagnostics
Colonic adenomas are considered a precursor of colorectal cancer. A 75-year-old woman had a history of post-operation left breast cancer. She received an excision when the left chest wall recurred.
Li-Yu Chen, Jong-Dar Chen, Yen-Kung Chen
doaj   +1 more source