Results 21 to 30 of about 346,835 (267)
Contribution of pks+ Escherichia coli (E. coli) to Colon Carcinogenesis
MicroorganismsColorectal cancer (CRC) stands as a significant global health concern, ranking second in mortality and third in frequency among cancers worldwide. While only a small fraction of CRC cases can be attributed to inherited genetic mutations, the majority ...
Mohammad Sadeghi +2 more
doaj +1 more source
An objective approach to assess colonic pain in mice using colonometry.
PLoS ONE, 2021 The present study presents a non-surgical approach to assess colonic mechanical sensitivity in mice using colonometry, a technique in which colonic stretch-reflex contractions are measured by recording intracolonic pressures during saline infusion into ...
Liya Y Qiao, Jonathan Madar
doaj +1 more source
Frontiers in OncologyPurposeThrough a pilot study, we performed whole gut metagenomic analysis in 17 Lynch syndrome (LS) families, including colorectal cancer (CRC) patients and their healthy first-degree relatives.
Mohammad Sadeghi +6 more
doaj +1 more source
Piezo2 regulates colonic mechanical sensitivity in a sex specific manner in mice
Nature Communications, 2023 The mechanosensitive ion channel Piezo2 in mucosa and primary afferents transduces colonic mechanical sensation. Here we show that chemogenetic activation or nociceptor-targeted deletion of Piezo2 is sufficient to regulate colonic mechanical sensitivity ...
Jonathan Madar +6 more
doaj +1 more source
The Turkish Journal of Gastroenterology, 2019 Background/Aims: Currently, right colonic uncomplicated diverticulitis is typically treated with antibiotic therapy. However, the optimal duration of treatment is unknown. The aim of the present study was to compare the treatment failure rates between 1-
Jung Ho Park +2 more
doaj +1 more source
Gut and Liver, 2020 Background/Aims: Endoscopic diagnosis of dysplasia or colitic cancer in patients with ulcerative colitis (UC) is more challenging than that of colorectal neoplasia in non-colitic patients. We aimed to evaluate the accuracy of the endoscopic diagnosis of “
Dong-Hoon Yang +13 more
doaj +1 more source
Colonic tuberculosis masquerading as colon cancer [PDF]
Journal of Surgical Case Reports, 2012 Isolated colonic tuberculosis (TB) is rare, and the symptoms are nonspecific making early diagnosis and management difficult. Although colonoscopy and biopsy is an important diagnostic modality, the features are variable and the distinction from other conditions of the colon, especially Crohn's disease and cancer, may be impossible without surgical ...
Kumar, A +3 more
openaire +2 more sources
Splenic flexure colonic lipoma causing intussusception
JRSM Open, 2021 Lesson Colonic lipomas are rare benign tumours that are usually asymptomatic. However, giant colonic lipomas tend to be symptomatic and can occasionally result in intussusception and intermittent colonic obstruction.
Moustafa Moussally +3 more
doaj +1 more source
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
Frontiers in OncologyColonic leiomyosarcoma (LMS) is a highly aggressive tumor arising from smooth muscle cells and is generally associated with a poor prognosis. This report presents a case of colonic LMS originating from the submucosal layer of the ascending colon.
Honghai Li +6 more
doaj +1 more source