Results 71 to 80 of about 1,115,426 (335)

Characterization of Human Colon Organoids From Inflammatory Bowel Disease Patients

Frontiers in Cell and Developmental Biology, 2020
Inflammatory Bowel Diseases (IBD) are chronic inflammatory disorders, where epithelial defects drive, at least in part, some of the pathology. We reconstituted human intestinal epithelial organ, by using three-dimension culture of human colon organoids ...
E. d’Aldebert, M. Quaranta, Morgane Sébert, D. Bonnet, S. Kirzin, G. Portier, J. Duffas, S. Chabot, P. Lluel, S. Allart, A. Ferrand, L. Alric, C. Racaud-Sultan, E. Mas, C. Deraison, N. Vergnolle   +15 more
semanticscholar   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

THE ANALYSIS OF THE REMOTE FUNCTIONAL RESULTS OF THE ELECTIVE COLONIC RESECTION AT DIVERTICULAR DISEASES

Koloproktologia, 2016
AIM. To evaluate long-term results of treatment of patients with the complicated diverticular diseases, after elective colonic resection. PATIENTS. The outcome of 53 patient operated on pretreated recurrent diverticulitis were compared to results of treatment of 50 patients with diverticulitis complicated by perforation and treated initially by ...
V. V. Khodakov, V. I. Pomazkin
openaire   +3 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Butyrate Mitigates Weanling Piglets From Lipopolysaccharide-Induced Colitis by Regulating Microbiota and Energy Metabolism of the Gut–Liver Axis

Frontiers in Microbiology, 2020
Inflammatory bowel disorder is accompanied by the destruction of immunity homeostasis, gut microbiota perturbation, and chronic inflammatory liver diseases.
Yunsheng Han, Yunsheng Han, Yunsheng Han, Qingyu Zhao, Qingyu Zhao, Chaohua Tang, Chaohua Tang, Ying Li, Ying Li, Kai Zhang, Kai Zhang, Fadi Li, Junmin Zhang, Junmin Zhang, Junmin Zhang   +14 more
doaj   +1 more source

A recursive function coding number theoretic functions [PDF]

arXiv, 2022
We show that there exists a fixed recursive function $e$ such that for all functions $h\colon \mathbb{N}\to \mathbb{N}$, there exists an injective function $c_h\colon \mathbb{N}\to \mathbb{N}$ such that $c_h(h(n))=e(c_h(n))$, i.e., $h=c_h^{-1}ec_h$.
arxiv  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Fecal Microbiota Transplantation Controls Murine Chronic Intestinal Inflammation by Modulating Immune Cell Functions and Gut Microbiota Composition

Cells, 2019
Different gastrointestinal disorders, including inflammatory bowel diseases (IBD), have been linked to alterations of the gut microbiota composition, namely dysbiosis.
Claudia Burrello, Maria Rita Giuffrè, Angeli Dominique Macandog, Angelica Diaz-Basabe, Fulvia Milena Cribiù, Gianluca Lopez, Francesca Borgo, Luigi Nezi, Flavio Caprioli, Maurizio Vecchi, Federica Facciotti   +10 more
doaj   +1 more source

Nanomaterials and nanoparticles: Sources and toxicity [PDF]

Published in Biointerphases Vol. 2, issue 4 (2007) pages MR17 - MR71, 2008
This review is written with the goal of informing public health concerns related to nanoscience, while raising awareness of nanomaterials toxicity among scientists and manufacturers handling them. We show that humans have always been exposed to nanoparticles and dust from natural sources and human activities, the recent development of industry and ...
arxiv  

Functional role of microRNA-135a in colitis

Journal of Inflammation, 2018
Inflammatory bowel disease (IBD) is one of the chronic gastrointestinal diseases with increasing risk of colon cancer development in the future. Apoptosis and inflammation play an important role in the etiology of this disease.
Chunyan Lou, Yanyang Li
semanticscholar   +1 more source