Results 121 to 130 of about 139,771 (224)

Aspartate Transporter SLC1A3 Promotes Colorectal Cancer via MDM2‐p53 Pathway and M2 Macrophage Polarization

open access: yesCancer Science, Volume 117, Issue 7, Page 1813-1827, July 2026.
SLC1A3 promotes colorectal cancer progression by transporting extracellular aspartate into tumor cells, thereby activating the PKC/MDM2/p53 pathway to enhance proliferation. Reduced extracellular aspartate, combined with p53‐dependent suppression of CSF2 and IL17C, drives M2 macrophage polarization via immune modulation, macrophage recruitment, and M2 ...
Chao Deng   +9 more
wiley   +1 more source

Real-Time Characterization of Colonic Polyps: A Multicenter Prospective Study Evaluating the CAD-EYE System in Screening Colonoscopies. [PDF]

open access: yesClin Transl Gastroenterol
Maigné M   +14 more
europepmc   +1 more source

Bifidobacterium bifidum G9‐1 Intake Improves Gastrointestinal Symptoms in Type 2 Diabetes Mellitus: An Open‐Label, Randomized Controlled Trial (Binary STAR Study)

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5952-5967, July 2026.
ABSTRACT Aims To evaluate the effects of probiotics Bifidobacterium bifidum G9‐1 (BBG9‐1) on gastrointestinal symptoms in patients with Type 2 diabetes mellitus (T2DM) with diarrhoea or constipation. Materials and Methods In a 12‐week open‐label randomised controlled trial, 100 participants were randomized 1:1 to a control or BBG9‐1 group, with 12 mg ...
Genki Kobayashi   +10 more
wiley   +1 more source

Dysplasia in sessile serrated lesions: frequency, interobserver variability and added value of immunohistochemistry

open access: yesHistopathology, Volume 89, Issue 1, Page 98-109, July 2026.
Sessile serrated lesions with dysplasia represent a critical step in colorectal carcinogenesis. While routine histologic diagnosis is generally reliable and positive diagnostic trends are observed, subtle dysplastic changes may be overlooked. Targeted use of MLH1 immunohistochemistry provides meaningful diagnostic support in selected sessile serrated ...
Valentina Angerilli   +9 more
wiley   +1 more source

Chronic ulcerative oesophagitis rich in IgG4‐positive plasma cells – a distinct clinicopathological entity

open access: yesHistopathology, Volume 89, Issue 1, Page 47-57, July 2026.
We report a series of 12 patients (mean age 63 years) with chronic oesophageal ulceration showing morphological features of IgG4‐related inflammatory disease. Most patients underwent several rounds of endoscopy until this association was recognized. The majority of patients went into clinical and histological remission following corticosteroid therapy.
Hanna Henzinger   +5 more
wiley   +1 more source

Colonic polyps with Ascaris Lumbricoides eggs. [PDF]

open access: yesIDCases
Ye Q   +5 more
europepmc   +1 more source

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