Shared risk factors, clinical features, and tumor characteristics across multiple early‐onset cancer types are shown in this Graphical Abstract. Integrative approaches combining molecular pathology, oncology, and population sciences offer opportunities to clarify underlying mechanisms and help us develop preventive strategies for early‐onset cancers ...
Nobuhiro Nakazawa +17 more
wiley +1 more source
Dysplasia and Malignancy in Colonic Polyps: Preparing for a Resect and Discard Strategy in Canada. [PDF]
Patel VV, Bechara R, Rai M.
europepmc +1 more source
Safety of endoscopic mucosal resection of large colonic polyps in elderly patients: a systematic review and meta-analysis. [PDF]
Iqbal U +8 more
europepmc +1 more source
ABSTRACT Aims Observational studies show metformin use associated with lower cancer risk, although experimental evidence is inconsistent. To provide genetic validation for repositioning of metformin in cancer prevention, we assessed genetically proxied effects of putative metformin targets on cancer outcomes using a drug‐target Mendelian randomization (
Xingyu Shen +7 more
wiley +1 more source
Colonic polyps in North-Western Romania: a comprehensive single-center analysis of endoscopic and pathological features. [PDF]
Albu A +6 more
europepmc +1 more source
Inhibitory Activity of Conferone on FAK Activity and Glutamine Metabolism in Human Colorectal Cancer
ABSTRACT Colorectal cancer (CRC) is a major global cause of death, with metastases and chemotherapy resistance contributing to poor outcomes. To identify natural compounds with anticancer potential against CRC and elucidate their action mechanisms, the cytotoxicity of 37 natural compounds was evaluated against the HCT116, leading to the identification ...
Hien Thi My Ong +5 more
wiley +1 more source
Enhanced visualization of colonic polyps using a fluorophore-conjugated claudin-1 antibody in a CPC-APC mouse model. [PDF]
Liu S +13 more
europepmc +1 more source
Random forests algorithm using basic medical data for predicting the presence of colonic polyps. [PDF]
Avram MF +6 more
europepmc +1 more source
Effects of intraduodenally applied bile salts on pancreatic secretion [PDF]
Lehnert, Peter, Riepl, Rudolf L.
core +1 more source
Objectives Canine chronic idiopathic rhinitis is a common cause of nasal disease in dogs but data reporting outcomes following treatment is lacking. The aim was to describe pre‐ and post‐referral management and outcomes of dogs diagnosed with canine chronic idiopathic rhinitis at a single referral centre.
P. M. N. Henry +5 more
wiley +1 more source

