Results 91 to 100 of about 191,870 (303)

Legal origin, colonial origin and deforestation [PDF]

This paper investigates whether inherited legacies such as legal origin allow of explaining deforestation in 110 developed and developing countries. The hypothesis is that differences in deforestation between countries can be attributed to their legal ...
Sébastien MARCHAND
core  

On the presence of the Ponto-Caspian hydrozoan Cordylophora caspia (Pallas, 1771) in an Iberian estuary: highlights on the introduction vectors and invasion routes [PDF]

, 2017
Several non-native invertebrate and vertebrate species have been detected in the Guadiana Estuary (SW-Iberian Peninsula, Europe) during the 21st century.
Amorim, Katherine, Leitão, Francisco, Martins, Flavio, Morais, Pedro, Seyer, Thomas, Teodosio, Maria   +5 more
core   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

William Robertson’s Unfinished History of America. The Foundation of the British Empire in North America and the Scottish Enlightenment

Transatlantica, 2019
Historian and clergyman William Robertson never completed his history of British America. His initial project, that of glorifying the power of the British Empire, no longer made sense when the Thirteen Colonies became independent. This paper analyses the
Florence Petroff
doaj   +1 more source

Inhibition of spontaneous and experimental lung metastasis of soft-tissue sarcoma by tumor-targeting Salmonella typhimurium A1-R. [PDF]

, 2014
Prognosis of patients with lung metastases of soft-tissue sarcoma is still poor. Therefore, novel systemic therapy is needed to improve the survival of soft-tissue sarcoma.
Baek, Kyung-Eun, Bouvet, Michael, Hayashi, Katsuhiro, Hiroshima, Yukihiko, Hoffman, Robert M, Kimura, Hiroaki, Matsumoto, Yasunori, Miwa, Shinji, Tsuchiya, Hiroyuki, Uehara, Fuminari, Yamamoto, Mako, Yamamoto, Norio, Yano, Shuya, Zhang, Yong, Zhao, Ming   +14 more
core   +3 more sources

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Biotimer assay: A reliable and rapid method for the evaluation of central venous catheter microbial colonization [PDF]

, 2017
Adherent bacteria and biofilm frequently colonize central venous catheters (CVCs). CVC colonization is correlated to infections and particularly to bloodstream ones.
Antimo Cutone, COLETTI, Monica, Francesca Berlutti, Giammarco Raponi, Luigi Rosa, Maria Cristina Ghezzi, Maria Stefania Lepanto, Piera Valenti, SCOTTI, MELLANI   +8 more
core   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

Baptists in the Religious Landscape of the Thirteen Colonies: Towards Religious Freedom and Diversity

Вестник Северного (Арктического) федерального университета: Серия «Гуманитарные и социальные науки»
The purpose of this article is to examine the influence of Baptist groups on the emergence of religious diversity and secularism during the colonial history of the United States. Baptism, which penetrated North America in the first decades of the English
Daniil V. Ivanov
doaj   +1 more source