Results 131 to 140 of about 2,774,341 (257)
Advanced Science, EarlyView.A CTGF‐LYTAC nanoplatform is developed to selectively degrade connective tissue growth factor (CTGF) in triple‐negative breast cancer (TNBC), inhibiting TGF‐β signaling and cell interactions in the tumor microenvironment (TME). This strategy effectively suppresses tumor growth and metastasis, outperforming antibody‐based therapy.
Jia‐Yi Lin +11 more
wiley +1 more source
How Does Colonial Origin Matter for Economic Performance in Sub-Saharan Africa? [PDF]
This paper investigates some of the existing hypotheses regarding the transmission of different colonial legacies to modern day economic growth. The fact that different colonial strategies were pursued by different colonizers in various territories ...
Julius A. Agbor
core
SMC4 Promotes Prostate Cancer Cell Proliferation and Metastasis via the Rheb/mTOR Pathway
Advanced Science, EarlyView.Structural maintenance of chromosome protein 4 (SMC4) has been implicated in prostate cancer metastasis. Knockdown of SMC4 in RM1‐LM cells significantly attenuates proliferation, migration, and lung metastasis in vivo. Furthermore, SMC4 interacts with GLUT1 (Slc2a1), thereby enhancing glycolysis, ATP production, and activation of the Rheb/mTOR pathway.
Wei Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.A multifunctional, edible, and hydrogel‐transformable probiotic powder is developed based on the “bacteria‐mediated bacterial eradication” strategy. By leveraging the targeted binding capability of L. reuteri to H. pylori, this approach achieves an integrated therapeutic effect, including bactericidality, anti‐inflammation, gastric mucosal repair, and ...
Yongkang Lai +9 more
wiley +1 more source
Advanced Science, EarlyView.This study introduces a novel therapeutic approach that employs a conductive hydrogel (HEPP) responsive to near‐infrared light, pH levels, and reactive oxygen species. Its goal is to enhance the healing environment affected by elevated glucose levels, insufficient oxygen, and bacterial infections in diabetes‐related wounds.
Tao Zhang +4 more
wiley +1 more source
Colonialism brought home: on the colonization of the metropolitan space
Departing from an appraisal of the topical relevance of what Canadian based geographer Derek Gregory has perceptively called 'the colonial present', this article presents a number of departures for an investigation of the ways in which the codes of a colonial conditions have infiltrated the metropolitan west (Gregory 2004).
openaire +1 more source
Advanced Science, EarlyView.During different developmental stages of plants in natural Se–Cd coexisting soils, there is a group of rhizosphere microorganisms with highly dynamic abundance. The abundance variation of these microorganisms is strongly positively correlated with available Se and strongly negatively correlated with available Cd.
Zheng Lei +16 more
wiley +1 more source
The Black Man's Burden - The cost of colonization of French West Africa for French taxpayers [PDF]
Was colonization very costly for the metropole? This view has been widely accepted among French historians even though little empirical evidence has been provided.
Elise Huillery
core
Advanced Science, EarlyView.This study develops a photosynthetic bioelectrochemical nitrogen fixation system for simultaneous nitrogen fixation and current generation using Rhodopseudomonas palustris. Notably, extracellular electron transfer (EET) serves as a redox balancing strategy, suppressing nitrogen fixation by competing with nitrogenase for electrons.
Xuewen Liu +6 more
wiley +1 more source