Results 131 to 140 of about 71,581 (290)

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

<i>Streptococcus agalactiae</i> colonization in pregnant women: which culture-based detection method is best? [PDF]

J Med Microbiol
Schoeler S, Theiler T, Möllers M, Olaru ID, Schuler F, Schaumburg F.   +5 more
europepmc   +1 more source

Intertidal Warfare: Synergistic Allelopathy Mediates Spatial Competition between Two Marine Calcareous‐Shelled Sessile Organisms

Advanced Science, EarlyView.
This study reveals a hidden chemical weapon among calcareous‐shelled sessile organisms in the intertidal zone: the barnacle Balanus albicostatus releases a synergistic blend of palmitic acid and 1‐palmitoyl‐sn‐glycero‐3‐phosphocholine as the allelochemical with the inhibitory activity against attachment of the mussel Vignadula atrata, which may mediate
Zhuo Li, Zixin Huo, Shanshan Yao, Xianmeng Liang, Yiran Zhao, Yanxin Wang, Shifeng Guo, Caihuan Ke, Pei Su, Danqing Feng   +9 more
wiley   +1 more source

RprR is a plant-responsive regulator of exopolysaccharide production, biofilm formation, and virulence in <i>Ralstonia pseudosolanacearum</i>. [PDF]

mBio
O'Banion BS, Carter MD, Sanchez-Gallego JA, Li H, Wagner N, Chu LT, Bui L, Tran TM, Allen C.   +8 more
europepmc   +1 more source

Effect of P. cattleianum aerial parts’ n-hexane extract (HE) and its selective sub-fractions on the colonies’ number (CN), and survival fraction (SF from control) in colonization assay.

Eman M. El-Deeb (14571719), Fatma A. Moharram (9276104), Hussein S. Taha (14571722), Mohamed R. Elgindi (14571725), Kuei-Hung Lai (3226101), Hassan Y. Ebrahim (3800953), Heba E. Elsayed (3800956)   +6 more
openalex   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Methylotrophic yeast <i>Candida boidinii</i> enhances the colonization of plant growth-promoting yeast <i>Papiliotrema laurentii</i> in the phyllosphere. [PDF]

Front Microbiol
Shigeta K, Shiraishi K, Schroll M, Lauer R, Keppler F, Sakai Y, Yurimoto H.   +6 more
europepmc   +1 more source

Crown, Colonizer, and Colonial Encounter in Exploration History [PDF]

Terrae Incognitae, 2019
openaire   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source