Results 41 to 50 of about 190,359 (307)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Le renouveau identitaire des colonies grecques à l’époque impériale : Ioniens et Doriens dans le Pont-Euxin

Cahiers Mondes Anciens, 2011
Two leading mother-cities are obvious during the colonization of the Black Sea : Miletus, or more generally Ionia, and Megara, with a Boiotian participation.
Madalina Dana
doaj   +1 more source

Everybody nose: molecular and clinical characteristics of nasal colonization during active methicillin-resistant Staphylococcus aureus bloodstream infection

BMC Infectious Diseases, 2022
Background Healthcare-associated infections pose a potentially fatal threat to patients worldwide and Staphylococcus aureus is one of the most common causes of healthcare-associated infections. S.
Erika Reategui Schwarz, Adriana van de Guchte, Amy C. Dupper, Ana Berbel Caban, Devika Nadkarni, Lindsey Fox, Alexandra Mills, Ajay Obla, Kieran I. Chacko, Irina Oussenko, Flora Samaroo, Jose Polanco, Richard Silvera, Melissa L. Smith, Gopi Patel, Melissa Gitman, Bremy Alburquerque, Marilyn Chung, Mitchell J. Sullivan, Harm van Bakel, Deena R. Altman   +20 more
doaj   +1 more source

Evaluating the capacity of human gut microorganisms to colonize the zebrafish larvae (Danio rerio) [PDF]

, 2018
Indexación: Scopus.In this study we evaluated if zebrafish larvae can be colonized by human gut microorganisms. We tested two strategies: (1) through transplantation of a human fecal microbiota and (2) by successively transplanting aerotolerant anaerobic
Angelica Reyes-Jara, Carmen G. Feijóo, Daniel A. Medina, Daniel Garrido, Fabien Magne, Guillermo Figueroa, Magaly Toro, Maria-Jose Valenzuela, Mario Caruffo, Maximo Coronado, Miriam Troncoso, Paola Navarrete, Salomé Muñoz, Yoani Herrera, Yoani Herrera   +14 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Digital Analysis of Mycelium Growth and Mycelium Density In Vitro of Pleurotus ostreatus with Submerged Fermentation as Substrate Treatment

Mycobiology
Edible mushroom cultivation often involves sterilizing the substrate, or a similar heat process like pasteurization, to facilitate mycelial colonization. Chemical treatments are an alternative approach that is also employed in some regions.
Jorge Andres Magaña Amaya, Naoto Shimizu   +1 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Evidence of rare occurrences of the Phoenix effect in the Hawaiian corals Porites compressa and Montipora capitata following mortality induced by a marine heatwave [PDF]

PeerJ
Coral bleaching is a common stress response to extreme temperatures experienced during marine heatwaves. Bleached corals are left vulnerable without the nutritional support of their algal symbionts, and can often suffer partial or complete mortality ...
Katelyn G. Jones, Katie L. Barott
doaj   +2 more sources

Cluster of legionnaires’ disease in an Italian prison [PDF]

, 2019
Background: Legionella pneumophila (Lp) is the most common etiologic agent causing Legionnaires’ Disease (LD). Water systems offer the best growth conditions for Lp and support its spread by producing aerosols.
Cala C., Capra G., Di Carlo P., Distefano S. A., Fasciana T., Giammanco A., Mascarella C., Palermo M., Rampulla A.   +8 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source