Results 41 to 50 of about 74,759 (262)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Development of a workflow for the detection of vancomycin-resistant Enterococcus faecium and Enterococcus faecalis from rectal swabs using the spectra VRE medium

Annals of Clinical Microbiology and Antimicrobials, 2023
Background Spectra™ VRE agar (Remel, Lenexa, KS) is a chromogenic agar that is FDA approved for screening patients for VRE colonization. The package insert recommends confirming isolates with identification and susceptibility testing, but confirming ...
Kendall Kling, Javier Rios, Laura Dirnberger, Wanda Polanco, Kevin Fritz, Michael Malczynski, Teresa Zembower, Chao Qi   +7 more
doaj   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Development of Multifunctional Hierarchically Restructured Antibacterial Neural Interfacing Electrodes via Plasma‐Enhanced Atomic Layer Deposition of Zinc Oxide Thin Films

Advanced Functional Materials, EarlyView.
ABSTRACT Next‐generation implantable neural‐interfacing devices are increasingly constrained by the coupled demands of electrode miniaturization, electrochemical performance, and implantation infection risk. Femtosecond laser–based hierarchical surface restructuring (HSR) technology has emerged as a scalable, manufacturing‐compatible platform for ...
Henna Khosla, Wesley Seche, Kriti Panchal, Steven J. May, Ekaterina Pomerantseva, Jacob Elmer, Tyler Cooper, Matthew J. Urban, Hailey Y. Maurer, Gregory A. Caputo, Jeffrey Hettinger, Shahram Amini, Gang Feng   +12 more
wiley   +1 more source

Infection and Infecting — the Key Moments of Infectious Disease Occurrence

Zdorovʹe Rebenka, 2014
Contact with foreign microorganisms in/on the human body leads to infection. This process is accompanied by the interaction of foreign microorganisms with human microbiota and factors of innate immunity.
I.V. Bogadelnikov, Ye.A. Kruger, A.V. Bobrysheva, N.I. Muzhetskaya   +3 more
doaj   +1 more source

One‐Step Curcumin‐Mediated Multiphoton Lithography for Bioactive 3D Scaffolds

Advanced Functional Materials, EarlyView.
Curcumin‐mediated multiphoton lithography enables one‐step fabrication of highly architected complex gelatin methacryloyl scaffolds by exploiting curcumin as a multifunctional bioactive photoinitiator. The resulting 3D structures support mesenchymal stem cell adhesion, proliferation, and migration, while exhibiting dual antibacterial activity through ...
Myrto Charitaki, Michalis Stavrou, Chrysanthi Pinelopi Apostolidou, Elmina Kabouraki, David Gray, Anna Mitraki, Anthi Ranella, Maria Farsari   +7 more
wiley   +1 more source

Minimal repeats are ubiquitous sites of crossover and recombination across the human genome

BMC Genomics
Background Crossover and recombination create genetic diversity that reflects differences in the DNA sequences of different organisms. We previously reported that trinucleotide 2-repeat units (T2Us) are sites of crossover and consequent colonization ...
Mina Ohadi, Nahid Tajeddin, Hadi Bayat, Dale J Annear, Ali M. A. Maddi, Hamid R. Khorram Khorshid, Kaveh Kavousi, Ahmad Delbari, Alireza Nikkhah, Masoud Arabfard   +9 more
doaj   +1 more source

Quantitative whole-tissue 3D imaging reveals bacteria in close association with mouse jejunum mucosa

npj Biofilms and Microbiomes, 2023
Because the small intestine (SI) epithelium lacks a thick protective mucus layer, microbes that colonize the thin SI mucosa may exert a substantial effect on the host.
Roberta Poceviciute, Said R. Bogatyrev, Anna E. Romano, Amanda H. Dilmore, Octavio Mondragón-Palomino, Heli Takko, Ojas Pradhan, Rustem F. Ismagilov   +7 more
doaj   +1 more source

Dynamically Actuated Reconfigurable Topographical Surface Enables Active Control of Implant‐Associated Infections

Advanced Functional Materials, EarlyView.
A dynamically actuated reconfigurable topographical surface (DARTS) integrates contact‐mediated bactericidal nanotopography with programmable mechanical actuation to actively disrupt bacterial biofilms. Dynamic surface reconfiguration enhances bacterial killing and suppresses implant‐associated infections in vivo, providing a new strategy for active ...
Mohammad Asadi Tokmedash, Jihun Lee, J. Scott VanEpps, Sungmin Nam, Jouha Min   +4 more
wiley   +1 more source

Education in the Colonies of the Jewish Colonization Association in Argentina [PDF]

SSRN Electronic Journal, 2016
The philanthropic activity of Baron de Hirsch was clearly marked by one characteristic: not providing charity but attempting the economic rehabilitation of the beneficiaries. Hirsch systematically suggests that education and professional training were the only way to break the vicious circle of poverty.
openaire   +2 more sources