Results 201 to 210 of about 242,775 (289)

ESBL-producing <i>Klebsiella pneumoniae</i> gut colonisation and subsequent health-care associated bacteraemia in preterm newborns: a descriptive cohort with nested case-control study. [PDF]

Epidemiol Infect
Benboubker M, Oumokhtar B, Oukachou D, Elfakir S, Belchkar S, Rossi M, Massik A, Yahyaoui G, Moutaouakkil K, Hmami F.   +9 more
europepmc   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Exploring the Muco-Microbiotic Interface as a Hub for Microbial Metabolites and Immune Regulation in Gastroenteric Health and Disease. [PDF]

Cells
Carista A, Gratie MI, Tornatore E, Accomando S, Tomasello G, Picone D, Burgio S, Cappello F.   +7 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Evaluation of microbiological efficacy of 2% chlorhexidine gluconate cloths versus 4% chlorhexidine gluconate soap for preoperative preparation/shower in total joint arthroplasty: a single-centre randomised controlled trial. [PDF]

Antimicrob Resist Infect Control
Gallouche M, Rubens-Duval B, Boisset S, Margotton M, Caspar Y, Le Maréchal M, Bosson JL, Astagneau P, Gauchet A, Landelle C.   +9 more
europepmc   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

Infection Dynamics and Host Biomarker Identification for Spotty Liver Disease in Chickens. [PDF]

Vet Sci
James H, Gan E, Moore RJ, Andrews DM, Van TTH.   +4 more
europepmc   +1 more source

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

Advanced Science, EarlyView.
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang, Qingxin Si, Zhiguo Chen, Zhe Yu, Zhan Guo, Lu Wang, Weixi Li, Wangzhen Guo   +7 more
wiley   +1 more source

Across the Channel and Through Time: Did Lesser Horseshoe Bats Colonise Pantelleria From Europe or North Africa? [PDF]

Ecol Evol
Cistrone L, Mori E, Baratti M, Ahmim M, Todaro S, Viviano A, Russo D.   +6 more
europepmc   +1 more source

Genomic features of the Helicobacter pylori strain PMSS1 and its virulence attributes as deduced from its in vivo colonisation patterns

, 2018
Alikhan, Arnold, Aspholm, Aziz, Backert, Backert, Bankevich, Barrozo, Bartfeld, Bauer, Belogolova, Bonsor, Cao, Censini, Deguchi, Dixon, Draper, Farnbacher, Fischer, Gall, Gaudet, Gomez-Duarte, Gressmann, Higashi, Ishijima, Israel, Jang, Javaheri, Koch, Kusters, Königer, Lai, Lee, Lind, Linz, Lowenthal, Odenbreit, Olbermann, Philpott, Salama, Schmitt, Stein, Talarico, Tammer, Tan, Treangen, Viala, Zimmermann   +47 more
core   +1 more source