Results 31 to 40 of about 92,822 (275)
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Original supplementary materials for the slow reader on the revolutionary period [PDF]
Thesis (Ed.M.)--Boston University ...
Arvanites, Marie +2 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
CONTRACTING OF FOREIGNERS DURING LAUNCHING THE PROJECT OF COLONISTS’RESETTLEMENT TO RUSSIA (1760s)
The article presents a comparative analysis of different kinds of contracts concluded du-ring the resettlement of foreign colonists to Russia in the 1760s.
Olga K Ermakova
doaj +1 more source
German Colonists on River Milky Waters of Taurida Province in First Third of 19th Century
The information from the materials of the General Land Survey of the Russian Empire in the first third of the 19th century about the German colonies based on the territory of the Melitopol district of the Tauride province is analyzed in the article.
L. G. Stepanova
doaj +1 more source
We acknowledge indebtedness to the historians and developers of Alaskana who preceded us and provided much of the information we have compiled into our account of the birth of a community.
Johnson, Hugh A., Stanton, Keith L.
core
The Perils of Proximity: The Geopolitical Underpinnings of Australian Views of New Caledonia in the Nineteenth Century [PDF]
In the nineteenth and early twentieth centuries the links between these far-flung outposts of empire, New Caledonia and Australia, were much stronger than we might realise today.
Rechniewski, Elizabeth
core +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
A social-ecological approach to characterize ecosystem services in the Ecuadorian Amazon
Social-ecological approaches are necessary to understand complex systems in which humans are dependent on ecosystem services to support their livelihoods.
Francisco Neira-Brito +6 more
doaj +1 more source

