Results 51 to 60 of about 92,822 (275)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Ученые записки Казанского университета: Серия Гуманитарные науки, 2018 The paper is devoted to the invitation of foreign colonists to Russia at the beginning of Catherine II’s reign. The purpose of the research is to reconstruct the initial stage of formation of colonization policy of the Russian Empire.
G.V. Ibneyeva, A.I. Lebedeva
doaj
Phoenician Seamen and Colonists codifying the African Atlantic Coast
Gerión, 2015 Phoenician Seamen and Colonists codifying the AfricanAtlantic ...
Fernando López Pardo
doaj +1 more source
Pleistocene occupation of the arid zone in Southeast Australia: Research prospects for the Cooper Creek-Strzelecki Desert Region [PDF]
, 1980 Archaeological evidence for the presence of people in southeastern Australia as early as 40,000 years ago in environments substantially different from the Southeast Asian homeland of the initial colonists of Greater Australia has generated much ...
Hughes, P J, Lampert, Ronald John
core
Extending an eco-evolutionary understanding of biofilm-formation at the air-liquid interface to community biofilms [PDF]
, 2020 Growing bacterial populations diversify to produce a number of competing lineages. In the Pseudomonas fluorescens SBW25 model system, Wrinkly Spreader mutant lineages, capable of colonising the air-liquid interface of static microcosms by biofilm ...
Jerdan, Robyn +4 more
core +3 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Swedish Journal of Romanian StudiesThis study underlines the fact that Freemasonry, brought to Banat by the Austrian settlers, did not leave this area as an isolated provincialism. It was in direct contact with the Central European elite, exchanging ideas and experiences.
Attila Carol Varga
doaj +1 more source
Aquatic beetles influence colonization of disparate taxa in small lentic systems
Ecology and Evolution, 2020 Structure of natural communities is shaped by both abiotic characteristics and the ongoing processes of community assembly. Important to this process are the habitat selection behaviors and subsequent survival of colonists, both in the context of ...
Matthew R. Pintar +1 more
doaj +1 more source
Migration and forests in the Peruvian Amazon: a review [PDF]
, 2019 This paper reviews the literature on the links between migration and forests in the Peruvian Amazon. It highlights not only the complexity of the migrant–forest interface in Peru but also the relative lack of research on these dynamics.
Cronkleton, Peter, Menton, Mary
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source