Results 71 to 80 of about 92,822 (275)

КОЛЕКТИВІЗАЦІЯ ТА ГОЛОД 1932–1933 РОКІВ У СПОГАДАХ ЄВРЕЙСЬКИХ КОЛОНІСТІВ ПІВДНЯ УКРАЇНИ [PDF]

open access: yesStorìnki Istorìï, 2014
The article is devoted to «oral history» materials about collectivization and hunger of 1932–1933 in the Jewish agricultural colonies of south of Ukraine. Themes of the different stages of collectivization and description of events of hunger of 1932–1933
Ю. М. Корогодський
doaj  

The Old Northwest Under British Control, 1763-1783 and Indiana A Part of the Old Northwest, 1783-1800 [PDF]

open access: yes, 1987
This handbook was developed to encourage more effective state citizenship through the teaching of state history. Attention is given to geographical factors, politics, government, social and economic changes, and cultural ...
Geib, George W.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Jeroen DeWulf, The Pinkster King and the King of Congo: The Forgotten History of America’s Dutch-Owned Slaves

open access: yesBMGN: Low Countries Historical Review, 2017
Jeroen DeWulf, The Pinkster King and the King of Congo: The Forgotten History of America’s Dutch-Owned Slaves (Jackson, Miss.: University of Mississippi Press, 2017, 320 pp., isbn 978 14 96 80881 3). 
Michael Douma
doaj   +1 more source

Scientific results of the Bryotrop expedition to Zaire and Rwanda : 7., life strategies of epiphytic bryophytes from tropical lowland and montane forests, ericaceous woodlands and the Dendrosenecio subpáramo of the eastern Congo basin and the adjacent mountains (Parc National de Kahuzi-Biega/Zaire, Forêt de Nyungwe/Rwanda) [PDF]

open access: yes, 1995
Life strategies of epiphytic bryophytes are studied along an altitudinal gradient from the eastern Congo basin (tropical lowland zone) to the mountains of the East-African graben (tropical subalpine/alpine Zone; BRYOTROP III-transect).
Frey, Wolfgang   +2 more
core  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Models suggesting field experiments to test two hypotheses explaining successional diversity [PDF]

open access: yes, 1998
A simple mathematical model of competition is developed that includes two alternative mechanisms promoting successional diversity. The first underpins the competition-colonization hypothesis in which early successional species are able to persist because
Pacala, S.W., Rees, M.
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy