Results 131 to 140 of about 884,810 (309)

Molecular Epidemiology and Antibacterial Susceptibility of Streptococci Isolated from Healthy Children Attending Day Care Units

Balkan Medical Journal, 2011
Objective: The aims of the study were to investigate antibacterial susceptibility and resistance mechanisms of streptococci isolated from healthy children attending day care units and to evaluate clonal relatedness of the strains.
Duygu Perçin, Bülent Bozdoğan, Demet Ayangil, Bülent Sümerkan, Peter C. Appelbaum   +4 more
doaj  

Real-time polymerase chain reaction (PCR) for Pneumocystis jirovecii detection in lower respiratory tract samples

Microbiology Spectrum
To date, the gold standard for Pneumocystis jirovecii pneumonia (PjP) diagnosis is direct microscopic examination (ME). However, several studies have shown that the DNA copy number of the P.
Federica Anna Maria Giardina, Marina Ramus, Francesca Campanini, Daniele Lilleri, Virginia Ferretti, Antonino Maria Guglielmo Pitrolo, Ambra Vola, Roberta Maserati, Fausto Baldanti, Stefania Paolucci   +9 more
doaj   +1 more source

COLONIC MALAKOPLAKIA

Journal of Ayub Medical College Abbottabad
This case report is of a 10-year-old female who presented with complaints of blood in her stool and colicky abdominal pain for the last 1.5 years. Biopsy samples from the rectum and left-sided colon were taken during a colonoscopy, revealing numerous histiocytes having calcified bodies (Michaelis-Gutmann bodies). Diagnosis of Malakoplakia was confirmed
Arit, Prakash, Noshaba, Noor, Ayesha, Marchant, Mariam, Ghori, Rameen Akhtar, Molani   +4 more
openaire   +2 more sources

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

BY ITS FRUITS? MYSTICAL AND VISIONARY STATES OF CONSCIOUSNESS OCCASIONED BY ENTHEOGENS

Zygon, 2014
A new era has emerged in research on entheogens largely due to clinical trials conducted at Johns Hopkins University and similar studies sponsored by the Council for Spiritual Practices.
doaj   +2 more sources

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

Precision Diagnosis of Helicobacter pylori Infection and Its Drug Resistance

iLABMED
Helicobacter pylori, a gram‐negative microaerophilic bacterium, is implicated in a broad spectrum of upper gastrointestinal disorders, including chronic gastritis, peptic ulcers, gastric cancer, and even certain extragastric diseases.
Bin Tang, Pu Li, Xuhu Mao
doaj   +1 more source

Phase Separation of NFIB Suppresses SLC3A2‐Mediated Ferroptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Castration‐resistant prostate cancer (CRPC) remains sensitive to ferroptosis, but its intrinsic resistance is poorly understood. Here, we identify NFIB as a master suppressor. SIRT7‐mediated NFIB acetylation drives its liquid–liquid phase separation, which promotes SLC3A2 transcription to inhibit ferroptosis.
Qiunuo Li, Danyang Chen, Yongzhen Xia, Yili Long, Nan Huang, Rongna Li, Mengting Shi, Mairehaba Kadier, Huafeng Luo, Xiaohui Chen, Hao Liu, Guanmin Jiang   +11 more
wiley   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

Advanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil, Maria Anezaki, Alexandros Simistiras, Stavros Glentis, Nikolaos Scarmeas, Pantelis Hatzis, Konstantinos Rouskas, Antigone S. Dimas   +7 more
wiley   +1 more source