Results 221 to 230 of about 1,127,670 (388)

Mechanistic Foundations of KRAS‐Driven Tumor Ecosystems: Integrating Crosstalk among Immune, Metabolic, Microbial, and Stromal Microenvironment

Advanced Science, EarlyView.
KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma, Shenao Fu, Jun Tan, Ying Han, Yihong Chen, Xiangying Deng, Hong Shen, Shan Zeng, Yinghui Peng, Changjing Cai   +9 more
wiley   +1 more source

Evidence of Mr. Jas. Fletcher, entomologist and botanist, Dominion Experimental Farms, before the Select Standing Committee of the House of Commons on Agriculture and Colonization, session of 1894

, 1895
James Fletcher, James Fletcher
openalex   +2 more sources

Vizcaíno and Spanish Expansion in the Pacific Ocean, 1580-1630San Francisco Bay. Discovery and Colonization, 1769-1776 [PDF]

, 1969
Richard E. Greenleaf
openalex   +1 more source

Fragment Autoantigens Stimulated T‐Cell‐Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine

Advanced Science, EarlyView.
A personalized whole tumor cell vaccine (FAST) is developed to address immunosuppressive tumor microenvironments and genomic instability‐driven heterogeneity. Irradiation and cryoablation‐treated tumor cells generate fragmented antigens (FAs) that activate broad‐spectrum antigen presentation via upregulated immunogenic cell death, MHC‐I, and damage ...
Yuan Li, Huiqin Chen, Qiaofeng Shen, Yingshuang Liu, Pingping Li, Yuqi Ma, Yugang Wang, Shengkai Li, Xueqing Yan, Liyu Liu, Jianwei Shuai, Min Wu, Qi Ouyang, Feng‐Ming (Spring) Kong, Gen Yang   +14 more
wiley   +1 more source

Pneumococcal colonization dynamics among young children with and without respiratory symptoms during the first year of the SARS-CoV-2 pandemic. [PDF]

PLoS One
Olarte L, Lee B, Banerjee D, Swanson DS, Harrison CJ, Selvarangan R.   +5 more
europepmc   +1 more source

Evidence of Mr. James Fletcher, entomologist and botanist, before the Select Standing Committee of the House of Common [sic] on Agriculture and Colonization, session of 1892

, 1892
James Fletcher, James Fletcher
openalex   +2 more sources

NPR1 Promotes Lipid Droplet Lipolysis to Enhance Mitochondrial Oxidative Phosphorylation and Fuel Gastric Cancer Metastasis

Advanced Science, EarlyView.
NPR1 induces lipolysis of stored lipid droplet and enhances mitochondrial oxidative phosphorylation to fuel gastric cancer metastasis. Specifically, NPR1‐mediated activation of PKG directly phosphorylates and activates HSL at Ser855 and Ser951, thereby driving lipolytic processes.
Huafeng Fu, Jie Zhang, Hengxing Chen, Haobin Hou, Huanjie Chen, Rongman Xie, Yanlei Chen, Jian Zhang, Dehua Liu, Leping Yan, Rui L. Reis, Joaquim M. Oliveira, Yulong He, Li Zhong, Qinbo Cai, Dongjie Yang   +15 more
wiley   +1 more source

Associations between total protein, globulin, and nasal Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA) colonization in US adults: results from the national health and nutrition examination survey 2001-2004. [PDF]

Front Immunol
Chen K, Feng X, Liu F, Fan Y, Zhang T, Wang H, Feng S.   +6 more
europepmc   +1 more source

Evidence of Mr. James Fletcher, entomologist and botanist, Dominion Experimental Farms, before the Select Standing Committee of the House of Commons on Agriculture and Colonization, session of 1896

, 1897
James Fletcher, James Fletcher
openalex   +2 more sources

Plaque Formation by Streptococci in an Artificial Mouth and Factors Influencing Colonization [PDF]

, 1977
C. Russell, W. A. Coulter
openalex   +1 more source