Results 41 to 50 of about 884,810 (309)

Residents or Tourists: Is the Lactating Mammary Gland Colonized by Residential Microbiota?

open access: yesMicroorganisms
The existence of the human milk microbiome has been widely recognized for almost two decades, with many studies examining its composition and relationship to maternal and infant health.
Ruomei Xu   +4 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Forças de transformação do ecossistema amazônico

open access: yesEstudos Avançados, 2005
NOS 470 anos iniciais da colonização da Amazônia brasileira, apenas 1% da área foi desmatada. Porém, nos últimos 35 anos (1970-2005) o desmatamento já atinge 17% da região e a população aumentou de dois milhões para mais de 20 milhões de habitantes. Hoje,
Antonia M. M. Ferreira, Enéas Salati
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

International law as primitive accumulation: Or, the secret of systematic colonization [PDF]

open access: yes, 2012
This article is available open access through the publisher’s website at the link below. Copyright © The Author, 2012.This article aims to bring the category of ‘primitive accumulation’ into the vocabulary of critical and Marxist international legal ...
Neocleous, M
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Factors affecting vancomycin-resistant Enterococcus faecium colonization of in-hospital patients in different wards

open access: yesTzu Chi Medical Journal
Objectives: The prevalence of vancomycin-resistant Enterococcus faecium (VRE) infection at a medical center in Eastern Taiwan rose to 80.6%, exceeding the average prevalence of 55.6% among all medical centers nationwide during the same period.
Yun-Cheng Wang   +3 more
doaj   +1 more source

A Gallus gallus Model for Determining Infectivity of Zoonotic Campylobacter

open access: yesFrontiers in Microbiology, 2019
To better understand public health implications of waterfowl as reservoirs for zoonotic sources of Campylobacter in recreational waters, we developed a Gallus gallus (chick) model of infection to assess the pathogenicity of environmental isolates of ...
Dennis Lye   +5 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Microborings in mid Cretaceous fish teeth [PDF]

open access: yes, 1999
Fish teeth and other remains from the British Cretaceous contain abundant evidence for post-mortem colonization by endolithic organisms. The borings are here recognised as occurring in three morphotypes, including a flask-shaped form not previously ...
Brett   +13 more
core   +1 more source

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