Results 121 to 130 of about 7,330 (189)
ABSTRACT Introduction The presence of colonic adenomatous polyps is a risk factor for colorectal cancer. Australian Guidelines changed in 2019 so that the surveillance colonoscopy intervals and polyp risk stratification were changed to reflect evidence available.
Yiu Ming Ho +2 more
wiley +1 more source
Surveillance After Pelvic Exenteration: A Systematic Review of Oncological and Functional Follow‐Up
ABSTRACT Background Surveillance following cancer surgery with curative intent serves the purpose of permitting early detection of recurrent disease in addition to monitoring and management of post‐resection functional sequelae. Although recommendations exist for most primary cancers, in the context of radical or re‐operative surgery such as pelvic ...
Adrian Hang Yue Siu +5 more
wiley +1 more source
National endoscopy data show that FIT‐based triage clearly outperforms symptom‐based referral for colorectal cancer risk stratification. FIT ≥ 10 identifies high‐risk symptomatic patients, while FIT < 10 confers very low cancer risk, supporting FIT as the primary tool for prioritising colonoscopy in symptomatic pathways.
David Beaton +4 more
wiley +1 more source
This study elucidates the pivotal regulatory role and mechanism of MLL1 in inflammatory bowel disease. Experimental data demonstrated elevated MLL1 expression levels in TNBS‐induced murine colitis models, with pharmacological inhibition of MLL1 significantly promoting recovery from CD‐like colitis by accelerating intestinal barrier restoration ...
Xue Song +12 more
wiley +1 more source
Abstract Aims To evaluate the effectiveness of combination therapy with sodium‐glucose cotransporter 2 (SGLT‐2) inhibitors and glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) compared with continued SGLT‐2 inhibitor therapy in routine practice among individuals with type 2 diabetes.
Gregor A. Maier +3 more
wiley +1 more source
Human papillomavirus‐associated adenoma of the anorectum
Aims Human papillomavirus (HPV) is the most common sexually transmitted disease in the United States. HPV‐associated invasive anorectal adenocarcinoma has been previously described. In this study, we report the clinicopathological features of three HPV‐associated anorectal adenomas.
Paula Toro +3 more
wiley +1 more source
Sessile serrated lesions with dysplasia represent a critical step in colorectal carcinogenesis. While routine histologic diagnosis is generally reliable and positive diagnostic trends are observed, subtle dysplastic changes may be overlooked. Targeted use of MLH1 immunohistochemistry provides meaningful diagnostic support in selected sessile serrated ...
Valentina Angerilli +9 more
wiley +1 more source
Inequities in inflammatory bowel disease care: a Tasmanian case study with proposed solutions
Abstract There is well‐recognised inequity of care for people treated with inflammatory bowel disease (IBD) between metropolitan and regional areas. We aim to describe these barriers to care using Tasmania as a case example and to suggest solutions for addressing these barriers that can be used in Tasmania and beyond.
Alexander T Elford +8 more
wiley +1 more source
ABSTRACT Background A novel bacterial gene marker, Lachnoclostridium (m3), has potential for non‐invasive diagnosis of colorectal cancer (CRC) and adenoma. Aim This study aims to determine the diagnostic performance of m3 in a multi‐center cohort and to examine the effect of diet and drugs on fecal m3 in subjects with colorectal neoplasia. Methods In a
Min Dai +10 more
wiley +1 more source

