Results 71 to 80 of about 175,064 (329)

Polyethylene glycol and prevalence of colorectal adenomas : Population-based study of 1165 patients undergoing colonoscopy [PDF]

, 2006
Background and aim — Dietary polyethylene glycol (PEG) is extraordinarily potent in the chemoprevention of experimental colon carcinogenesis. PEG is used to treat constipation in France and in the USA. French laxatives include Forlax® (PEG4000), Movicol®
Barbieux, Jean-Pierre, Bertrand, Philippe, Bougnoux, Philippe, Brondin, Brigitte, Corpet, Denis E., Dorval, Etienne, Jankowski, Jean Marie, Viguier, Jérôme   +7 more
core  

KLK1 as an Epithelial‐Specific Brake Inhibits Colorectal Tumorigenesis by Suppressing B1R‐Mediated Fibroblast Phenotypic Transition

Advanced Science, EarlyView.
KLK1 downregulation disrupts the intestinal mucosal barrier and impairs kallikrein‐kinin signaling, thereby reducing Lys‐des‐Arg9‐BK production. This enhances B1R activation on ADAMDEC1⁺ fibroblasts, promoting inflammation and extracellular matrix (ECM) remodeling. The resulting iCAFs promote colorectal cancer progression, highlighting a novel KLK1‐B1R
Lisha Zhou, Meijing Wang, Shunji Liu, Limei Gu, Shijia Liu, Qianming Du, Tianyi Zhang, Yinuo Ma, Lixin Zhao, Jiaming Wang, Qiang Xu, Tingsheng Ling, Haibo Cheng, Hongqi Chen, Yang Sun   +14 more
wiley   +1 more source

Preliminary Experience Using Full-Spectrum Endoscopy for Colorectal Cancer Screening: Matched Case Controlled Study

Gastroenterology Research and Practice, 2016
Background/Aim. High-quality colonoscopy is needed to reduce the morbidity and mortality of colorectal cancer. Full-spectrum endoscopy (FUSE) has recently shown potential in improving adenoma detection during colonoscopy. This study aimed to evaluate the
Sayo Ito, Kinichi Hotta, Kenichiro Imai, Masao Yoshida, Kimihiro Igarashi, Yuichiro Yamaguchi, Kohei Takizawa, Naomi Kakushima, Masaki Tanaka, Noboru Kawata, Hiroyuki Matsubayashi, Hirotoshi Ishiwatari, Hiroyuki Ono   +12 more
doaj   +1 more source

7‐Ketodeoxycholic Acid Promotes Colonic Mucosal Healing by Inducing Calcium Release from Endoplasmic Reticulum via the TGR5‐IP3R Pathway

Advanced Science, EarlyView.
7‐KDCA functions by driving intestinal epithelial cell migration through induction of calcium release from the endoplasmic reticulum. The findings emphasize a previously unrecognized property of 7‐KDCA in regulating cell migration, a required process for effective epithelial restitution and repair that is particularly critical for patients with UC to ...
Jing Zhang, Feng Jiang, Wenxin Xia, Yilei Guo, Yanrong Zhu, Mianjiang Zhao, Lingzi Xiao, Zhifeng Wei, Yufeng Xia, Yue Dai   +9 more
wiley   +1 more source

Identification of Risk Factors in Postoperative Urinary Dysfunction for Rectal Gastrointestinal Stromal Tumors

Annals of Gastroenterological Surgery, EarlyView.
Our study aimed to identify the incidence of risk factors for postoperative urinary dysfunction during surgery for rectal gastrointestinal stromal tumors. ABSTRACT Aim Curative resection and organ preservation are important to manage rectal gastrointestinal stromal tumors; however, postoperative quality of life, including urinary function, remains a ...
Jun Kataoka, Yuichiro Tsukada, Masashi Wakabayashi, Daichi Kitaguchi, Hiro Hasegawa, Koji Ikeda, Yuji Nishizawa, Masaaki Ito   +7 more
wiley   +1 more source

Colorectal Cancer Screening Quality Improvement: A FITKit Mailing Initiative [PDF]

, 2019
According to the American Cancer Society, colorectal cancers are diagnosed in 1 in 22 men and 1 in 24 women in their lifetime. Despite the wide range of effective CRC screening options available in the US, the Hudson Headwaters Health Network (HHHN) has ...
Kratzer, Isabella
core   +1 more source

Patient‐Reported Outcomes and Surgical Results of Hand‐Sewn Versus Stapled Anastomosis for Lower Rectal Cancer Located 4–5 cm From the Anal Verge: A Subanalysis of the Ultimate Study

Annals of Gastroenterological Surgery, EarlyView.
Preserving anorectal function while ensuring oncological success is critical in lower rectal cancer surgery. This multicenter prospective study compared hand‐sewn and stapled anastomosis in 135 patients with tumors 4–5 cm from the anal verge. Although post‐operative complications and oncological outcomes were similar, stapled anastomosis consistently ...
Masakatsu Numata, Jun Watanabe, Yuichiro Tsukada, Yusuke Suwa, Yosuke Fukunaga, Yasumitsu Hirano, Kazuhiro Sakamoto, Hiroki Hamamoto, Masanori Yoshimitsu, Hisanaga Horie, Nobuhisa Matsuhashi, Yoshiaki Kuriu, Shuntaro Nagai, Madoka Hamada, Shinichi Yoshioka, Shinobu Ohnuma, Tamuro Hayama, Koki Otsuka, Yusuke Inoue, Kazuki Ueda, Yuji Toiyama, Satoshi Maruyama, Shigeki Yamaguchi, Keitaro Tanaka, Takeshi Naitoh, Masahiko Watanabe, Motoko Suzuki, Toshihiro Misumi, Masaaki Ito, Ultimate Trial Group in Japan Society of Laparoscopic Colorectal Surgery   +29 more
wiley   +1 more source

Completion of Colonoscopy After Positive Fecal Occult Blood Test Screening at a Community Health Center

JGH Open
Introduction Screening for colorectal cancer decreases mortality. Fecal occult blood testing (FOBT) decreases some barriers to screening, however positive results require colonoscopy.
Niraj Gowda, Tatiana Rugeles Suarez, Chike Leigh, Lindsey Bierle, Michael Harring, Martin Maldonado‐Puebla, Sean M. Lee, Neeral Shah, Jillian S. Catalanotti   +8 more
doaj   +1 more source

Multivariable models for advanced colorectal neoplasms in screen-eligible individuals at low-to-moderate risk of colorectal cancer: towards improving colonoscopy prioritization

BMC Gastroenterology, 2021
Background Advanced colorectal neoplasms (ACNs), including colorectal cancers (CRC) and high-risk adenomas (HRA), are detected in less than 20% of persons aged 50 years or older who undergo colonoscopy.
Sanjay K. Murthy, Lilia Antonova, Catherine Dube, Eric I. Benchimol, Gregoire Le Gal, Richard Hae, Stephen Burke, Tim Ramsay, Alaa Rostom   +8 more
doaj   +1 more source

Improving the Patient Colonoscopy Prep Experience [PDF]

, 2017
AIM: To improve patient prep compliance, prep quality, and an overall better experience by designing a prep specific website that will address the most common prep questions and concerns Once launched, the website address will be placed on printed ...
Cohen, MD, Robert, Cosgrove, MD, Natalie, Dargan, MD, Andrew, Dhanekula, MD, Raja K., Francis, MD, Gloria, Gandhi, MD, Komal, Kistler, MD, Andrew, Malamood, MD, Mark, Moleski, MD, Stephanie M., Niu, MD, Bolin, Prieto, MD, Jorge, Reddy, MD, Sheela S., Shah, MD, Apeksha, Tofani, MD, Christina, Zabolotsky, MD, Andrew   +14 more
core   +1 more source