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Differential regulation of microglial states by colony stimulating factors [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2023
Recent studies have emphasized the role of microglia in the progression of many neurodegenerative diseases. The colony stimulating factors, CSF-1 (M-CSF), granulocyte-macrophage CSF (GM-CSF) and granulocyte CSF (G-CSF) regulate microglia through ...
E. Richard Stanley   +3 more
doaj   +2 more sources

Focal Adhesion Kinase and Colony Stimulating Factors: Intestinal Homeostasis and Innate Immunity Crosstalk [PDF]

open access: yesCells
Thousands struggle with acute and chronic intestinal injury due to various causes. Epithelial intestinal healing is dependent on phenotypic transitions to a mobile phenotype.
Nicholas D. Brown   +1 more
doaj   +2 more sources

Cholesterol loading suppresses the atheroinflammatory gene polarization of human macrophages induced by colony stimulating factors [PDF]

open access: yesScientific Reports, 2021
In atherosclerotic lesions, blood-derived monocytes differentiate into distinct macrophage subpopulations, and further into cholesterol-filled foam cells under a complex milieu of cytokines, which also contains macrophage-colony stimulating factor (M-CSF)
Jani Lappalainen   +5 more
doaj   +2 more sources

Myeloid Colony Stimulating Factors as Regulators of Macrophage Polarization [PDF]

open access: yesFrontiers in Immunology, 2014
The scope of functional heterogeneity in macrophages has been defined by two polarized end states known as M1 and M2, which exhibit the pro-inflammatory activities necessary for host defense and the tissue repair activities required for tissue repair ...
Thomas A Hamilton
doaj   +2 more sources

The use of granulocyte colony-stimulating factors in the management of breast cancer patients [PDF]

open access: yesFrontiers in Oncology
The dynamic development of oncology poses new challenges to health care practitioners (HCPs), related to the introduction of modern targeted therapies, immunotherapies, or new chemotherapy regimens.
Anna Bałata   +3 more
doaj   +2 more sources

Colony Stimulating Factors in Early Feline Infectious Peritonitis Virus Infection of Monocytes and in End Stage Feline Infectious Peritonitis; A Combined In Vivo And In Vitro Approach [PDF]

open access: yesPathogens, 2020
Feline coronavirus (FCoV) infection initiates monocyte-associated viremia and viral persistence. Virus-infected, -activated monocytes also trigger feline infectious peritonitis (FIP), a fatal systemic disease of felids typified by granulomatous (peri ...
Alexandra J. Malbon   +6 more
doaj   +2 more sources

Colony-stimulating factors detected in tumor cells and voided urine are potential prognostic markers for patients with muscle-invasive bladder cancer undergoing radical cystectomy [PDF]

open access: yesResearch and Reports in Urology, 2018
Yosuke Morizawa,1 Makito Miyake,1 Keiji Shimada,2 Shunta Hori,1 Yoshihiro Tatsumi,1 Yasushi Nakai,1 Nobumichi Tanaka,1 Tomomi Fujii,3 Kiyohide Fujimoto1 1Department of Urology, Nara Medical University, Nara, Japan; 2Department of Pathology, Nara City ...
Morizawa Y   +8 more
doaj   +2 more sources

Prophylaxis and management of chemotherapy-induced febrile neutropenia: The role of myeloid growth factors [PDF]

open access: yesMedicinski Podmladak, 2022
Febrile neutropenia is a serious chemotherapy-related adverse event that can lead to complications and death and it could be a significant burden on the organization of the health care system.
Dimitrijević Jelena, Stojanović Marko
doaj   +1 more source

Cytokine Patterns in Maternal Serum From First Trimester to Term and Beyond

open access: yesFrontiers in Immunology, 2021
Pregnancy implies delicate immunological balance between two individuals, with constant changes and adaptions in response to maternal capacity and fetal demands.
Anders Hagen Jarmund   +21 more
doaj   +1 more source

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